Intravenous Preload of Mesenchymal Stem Cells Rescues Erectile Function in a Rat Model of Cavernous Nerve Injury
Takayanagi A, Sasaki M, Kataoka-Sasaki Y, Kobayashi K, Matsuda Y, Oka S, Masumori N, Kocsis JD, Honmou O. Intravenous Preload of Mesenchymal Stem Cells Rescues Erectile Function in a Rat Model of Cavernous Nerve Injury. The Journal Of Sexual Medicine 2015, 12: 1713-1721. PMID: 26211660, DOI: 10.1111/jsm.12957.Peer-Reviewed Original ResearchConceptsMajor pelvic ganglionGlia cell-derived neurotrophic factorArterial pressureCN injuryErectile dysfunctionIntracavernous pressureMesenchymal stem cellsMSC groupErectile functionDMEM groupNeurotrophic factorCavernous nerve injury modelMale Sprague-Dawley ratsNerve injury modelPotential preventive effectMale SD ratsImportant neurotrophic factorSprague-Dawley ratsReal-time quantitative real-time polymerase chain reactionExpression levelsReal-time polymerase chain reactionQuantitative real-time polymerase chain reactionMRNA expression levelsPelvic gangliaPolymerase chain reaction