Mesenchymal stem cells: therapeutic outlook for stroke
Honmou O, Onodera R, Sasaki M, Waxman SG, Kocsis JD. Mesenchymal stem cells: therapeutic outlook for stroke. Trends In Molecular Medicine 2012, 18: 292-297. PMID: 22459358, DOI: 10.1016/j.molmed.2012.02.003.Peer-Reviewed Original ResearchConceptsMarrow-derived mesenchymal stem cellsTransplanted MSCsSpinal cord injuryInitial clinical studiesInitial human studiesBone marrow-derived mesenchymal stem cellsAdult bone marrow-derived mesenchymal stem cellsAdult human bone marrowAxonal sproutingCerebral ischemiaClinical outcomesNeuroprotective effectsCord injuryHuman bone marrowClinical studiesTherapeutic effectStroke modelAnimal modelsHuman studiesBone marrowMesenchymal stem cellsIntravenous deliveryTherapeutic outlookMSC deliveryStroke