Potential of olfactory ensheathing cells for cell-based therapy in spinal cord injury
Radtke C, Sasaki M, Lankford KL, Vogt PM, Kocsis JD. Potential of olfactory ensheathing cells for cell-based therapy in spinal cord injury. The Journal Of Rehabilitation Research And Development 2008, 45: 141-152. PMID: 18566933, DOI: 10.1682/jrrd.2007.03.0049.Peer-Reviewed Original ResearchConceptsSpinal cord injuryPeripheral nervous systemCentral nervous systemCord injuryAxonal regenerationNervous systemTreatment of SCIContusive spinal cord injuryPotential of olfactoryPermanent neurological deficitsSpecialized glial cellsCell therapy approachesCell transplantation approachesOEC biologyAxonal lossNeurological deficitsCell-based therapiesFunctional outcomeGlial cellsClinical studiesComplex lesionsMedicine cliniciansMacrophage activationTransplantation approachesInhibitory molecules18 MULTIPLE SCLEROSIS: REMYELINATION
KOCSIS J, SASAKI M, LANKFORD K, RADTKE C. 18 MULTIPLE SCLEROSIS: REMYELINATION. 2008, 413-435. DOI: 10.1016/b978-012373994-0.50020-8.Peer-Reviewed Original ResearchMyelin-forming cellsMultiple sclerosisConduction abnormalitiesPotential neuroprotective effectsProminent pathological featurePeripheral nervous systemEndogenous progenitor cellsPotassium channel distributionRemyelinated axonsIon channel organizationDemyelinated lesionsNeuroprotective effectsAxonal transectionPathological featuresFunctional deficitsMyelin repairAxonal repairMyelin resultsNervous systemImpulse conductionProgenitor cellsRemyelinationSclerosisTransectionAbnormalities