2018
Detection of local and remote cellular damage caused by spinal cord and peripheral nerve injury using a heat shock signaling reporter system
Hashimoto-Torii K, Sasaki M, Chang YW, Hwang H, Waxman SG, Kocsis JD, Rakic P, Torii M. Detection of local and remote cellular damage caused by spinal cord and peripheral nerve injury using a heat shock signaling reporter system. IBRO Neuroscience Reports 2018, 5: 91-98. PMID: 30480161, PMCID: PMC6240805, DOI: 10.1016/j.ibror.2018.11.003.Peer-Reviewed Original ResearchPeripheral nerve injurySpinal cordNerve injuryPeripheral nerve injury resultsAltered electrophysiological propertiesNerve injury resultsSecondary damageHeat shock factor 1Neuropathic painInjury resultsInjury siteClinical abnormalitiesShock factor 1Mouse modelMemory dysfunctionElectrophysiological propertiesCordFactor 1Cellular damageFurther deteriorationInjuryReporter systemAbnormalitiesImmediate stress responseCells
2017
Intravenous Infusion of Bone Marrow–Derived Mesenchymal Stem Cells Reduces Erectile Dysfunction Following Cavernous Nerve Injury in Rats
Matsuda Y, Sasaki M, Kataoka-Sasaki Y, Takayanagi A, Kobayashi K, Oka S, Nakazaki M, Masumori N, Kocsis JD, Honmou O. Intravenous Infusion of Bone Marrow–Derived Mesenchymal Stem Cells Reduces Erectile Dysfunction Following Cavernous Nerve Injury in Rats. Sexual Medicine 2017, 6: 49-57. PMID: 29275062, PMCID: PMC5815969, DOI: 10.1016/j.esxm.2017.10.005.Peer-Reviewed Original ResearchMajor pelvic ganglionBone marrow-derived MSCsMarrow-derived mesenchymal stem cellsPostoperative erectile dysfunctionCavernous nerve injuryErectile dysfunctionCN injuryIntravenous infusionVehicle groupMSC groupIntracavernous pressureMesenchymal stem cellsNerve injuryBone marrowNeurotrophic factor expression levelsBrain-derived neurotrophic factorMale Sprague-Dawley ratsFluorogold-positive neuronsSmooth muscle atrophyPotential therapeutic effectsStem cellsSprague-Dawley ratsExpression levelsReal-time polymerase chain reactionBone marrow-derived mesenchymal stem cells
2015
41 Preload of mesenchymal stem cells via intravenous infusion prevents erectile dysfunction in a rat model of cavernous nerve injury
Takayanagi A, Sasaki M, Kataoka-Sasaki Y, Kobayashi K, Matsuda Y, Oka S, Masumori N, Honmou O. 41 Preload of mesenchymal stem cells via intravenous infusion prevents erectile dysfunction in a rat model of cavernous nerve injury. European Urology Open Science 2015, 14: e41. DOI: 10.1016/s1569-9056(15)60044-6.Peer-Reviewed Original Research