Intravenous Infusion of Bone Marrow–Derived Mesenchymal Stem Cells Reduces Erectile Dysfunction Following Cavernous Nerve Injury in Rats
Matsuda Y, Sasaki M, Kataoka-Sasaki Y, Takayanagi A, Kobayashi K, Oka S, Nakazaki M, Masumori N, Kocsis JD, Honmou O. Intravenous Infusion of Bone Marrow–Derived Mesenchymal Stem Cells Reduces Erectile Dysfunction Following Cavernous Nerve Injury in Rats. Sexual Medicine 2017, 6: 49-57. PMID: 29275062, PMCID: PMC5815969, DOI: 10.1016/j.esxm.2017.10.005.Peer-Reviewed Original ResearchMajor pelvic ganglionBone marrow-derived MSCsMarrow-derived mesenchymal stem cellsPostoperative erectile dysfunctionCavernous nerve injuryErectile dysfunctionCN injuryIntravenous infusionVehicle groupMSC groupIntracavernous pressureMesenchymal stem cellsNerve injuryBone marrowNeurotrophic factor expression levelsBrain-derived neurotrophic factorMale Sprague-Dawley ratsFluorogold-positive neuronsSmooth muscle atrophyPotential therapeutic effectsStem cellsSprague-Dawley ratsExpression levelsReal-time polymerase chain reactionBone marrow-derived mesenchymal stem cells