2017
Genomic risk prediction of aromatase inhibitor‐related arthralgia in patients with breast cancer using a novel machine‐learning algorithm
Reinbolt R, Sonis S, Timmers C, Fernández‐Martínez J, Cernea A, de Andrés‐Galiana E, Hashemi S, Miller K, Pilarski R, Lustberg M. Genomic risk prediction of aromatase inhibitor‐related arthralgia in patients with breast cancer using a novel machine‐learning algorithm. Cancer Medicine 2017, 7: 240-253. PMID: 29168353, PMCID: PMC5773952, DOI: 10.1002/cam4.1256.Peer-Reviewed Original Research
2015
Risk factors for anthracycline-associated cardiotoxicity
Reinbolt R, Patel R, Pan X, Timmers C, Pilarski R, Shapiro C, Lustberg M. Risk factors for anthracycline-associated cardiotoxicity. Supportive Care In Cancer 2015, 24: 2173-2180. PMID: 26563179, PMCID: PMC4874738, DOI: 10.1007/s00520-015-3008-y.Peer-Reviewed Original ResearchConceptsSingle nucleotide polymorphismsAnthracycline cardiotoxicityRisk factorsAlcoholic drinks/weekFemale breast cancer patientsHigher cardiotoxicity riskDrinks/weekModerate alcohol consumptionAnthracycline-associated cardiotoxicityBreast cancer patientsCases of cardiotoxicityMajor alleleEjection fractionPediatric patientsCancer patientsCardiotoxicity riskLower riskTherapeutic strategiesAlcohol consumptionCardiotoxicityMultivariate analysisLogistic regressionPatientsGenomic predictorsSignificant correlation