2023
Sensorimotor Cortical Thickness Changes Following Taxane-Based Chemotherapy: Support for a CNS Role in CIPN?
Worthen-Chaudhari L, Monfort S, Chaudhari A, Lustberg M. Sensorimotor Cortical Thickness Changes Following Taxane-Based Chemotherapy: Support for a CNS Role in CIPN? Archives Of Physical Medicine And Rehabilitation 2023, 104: e51. DOI: 10.1016/j.apmr.2022.12.148.Peer-Reviewed Original ResearchChemotherapy cyclesCortical thicknessBrain changesBreast cancerSensorimotor regionsCycles of TaxolSensorimotor cortical thicknessChemotherapy-induced neuropathyFirst chemotherapy cycleBreast cancer survivorsMain outcome measuresMean cortical thicknessSensory-motor regionsBrain structural integrityTaxane exposureChemotherapy exposureCancer survivorsCentral effectsChemotherapy treatmentDesign ProspectiveOutpatient oncologyCNS roleCommencement of studyOutcome measuresGait variability
2017
Gait, balance, and patient-reported outcomes during taxane-based chemotherapy in early-stage breast cancer patients
Monfort S, Pan X, Patrick R, Ramaswamy B, Wesolowski R, Naughton M, Loprinzi C, Chaudhari A, Lustberg M. Gait, balance, and patient-reported outcomes during taxane-based chemotherapy in early-stage breast cancer patients. Breast Cancer Research And Treatment 2017, 164: 69-77. PMID: 28374323, PMCID: PMC5510549, DOI: 10.1007/s10549-017-4230-8.Peer-Reviewed Original ResearchConceptsBreast cancer patientsPatient-reported outcomesTaxane-based chemotherapyCancer patientsChemotherapy cyclesEarly-stage breast cancer patientsPatient-reported symptom severityDevelopment of CIPNSubsequent chemotherapy cyclesFirst chemotherapy cyclePatient-reported symptomsDose-limiting toxicityOutpatient oncology clinicsSelf-reported symptomsTaxane infusionTaxane therapyTaxane treatmentCIPN symptomsDose intensityPeripheral neuropathyOncology clinicPatient functionPhysical functionFunctional deficitsGait testing
2016
Natural history of postural instability in breast cancer patients treated with taxane-based chemotherapy: A pilot study
Monfort S, Pan X, Patrick R, Singaravelu J, Loprinzi C, Lustberg M, Chaudhari A. Natural history of postural instability in breast cancer patients treated with taxane-based chemotherapy: A pilot study. Gait & Posture 2016, 48: 237-242. PMID: 27341530, PMCID: PMC4969166, DOI: 10.1016/j.gaitpost.2016.06.011.Peer-Reviewed Original ResearchConceptsBreast cancer patientsTaxane-based chemotherapyCancer patientsPostural instabilityChemotherapy cyclesBalance impairmentNatural historyCOP excursionPilot studyCoP ellipse areaSubsequent chemotherapy cyclesFirst chemotherapy cycleEyes-closed conditionTaxane exposureTaxane infusionEllipse areaOncology clinicConfidence ellipse areaPatient populationChemotherapy treatmentAdverse symptomsBreast cancerBaseline valuesEffective treatmentSide effects