2023
Quantitative cardiovascular magnetic resonance findings and clinical risk factors predict cardiovascular outcomes in breast cancer patients
Kwan J, Arbune A, Henry M, Hu R, Wei W, Nguyen V, Lee S, Lopez-Mattei J, Guha A, Huber S, Bader A, Meadows J, Sinusas A, Mojibian H, Peters D, Lustberg M, Hull S, Baldassarre L. Quantitative cardiovascular magnetic resonance findings and clinical risk factors predict cardiovascular outcomes in breast cancer patients. PLOS ONE 2023, 18: e0286364. PMID: 37252927, PMCID: PMC10228774, DOI: 10.1371/journal.pone.0286364.Peer-Reviewed Original ResearchConceptsBreast cancer patientsSystolic heart failureCardiovascular outcomesCancer patientsHeart failureValvular diseaseStrain abnormalitiesLeft ventricular ejection fraction reductionCancer treatment-related cardiotoxicityCardiovascular magnetic resonance findingsVentricular ejection fraction reductionYale-New Haven HospitalEjection fraction reductionTreatment-related cardiotoxicityAdverse cardiovascular outcomesClinical risk factorsNormal LV functionGlobal longitudinal strainIschemic heart diseaseMagnetic resonance findingsRisk regression modelsNew Haven HospitalSubclinical cardiotoxicityDiastolic dysfunctionStatin use
2018
Usefulness of Integrating Heart Failure Risk Factors Into Impairment of Global Longitudinal Strain to Predict Anthracycline-Related Cardiac Dysfunction
Milks M, Velez M, Mehta N, Ishola A, Van Houten T, Yildiz V, Reinbolt R, Lustberg M, Smith S, Orsinelli D. Usefulness of Integrating Heart Failure Risk Factors Into Impairment of Global Longitudinal Strain to Predict Anthracycline-Related Cardiac Dysfunction. The American Journal Of Cardiology 2018, 121: 867-873. PMID: 29454478, DOI: 10.1016/j.amjcard.2017.12.022.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnthracyclinesAntibiotics, AntineoplasticAntineoplastic Agents, ImmunologicalAtrial FibrillationAtrial FlutterBreast NeoplasmsCoronary Artery DiseaseDiabetes MellitusDoxorubicinEchocardiographyFemaleHeart FailureHumansHypertensionLogistic ModelsMiddle AgedRenal InsufficiencyReproducibility of ResultsRetrospective StudiesRisk AssessmentRisk FactorsStroke VolumeTrastuzumabVentricular DysfunctionConceptsCancer therapeutics-related cardiac dysfunctionGlobal longitudinal strainRisk factorsEchocardiographic variablesCardiac dysfunctionLongitudinal strainImaging assessmentCertain clinical risk factorsHeart failure risk factorsVentricular global longitudinal strainLeft ventricular longitudinal strainClinical risk factorsLV ejection fractionVentricular longitudinal strainHigh-risk groupRisk prediction toolsFailure risk factorsReceiver-operating characteristicClinical factorsEjection fractionOncologic treatmentLV functionRetrospective studyClinical variablesBreast cancer