2015
Association between guideline recommended drugs and death in older adults with multiple chronic conditions: population based cohort study
Tinetti ME, McAvay G, Trentalange M, Cohen AB, Allore HG. Association between guideline recommended drugs and death in older adults with multiple chronic conditions: population based cohort study. The BMJ 2015, 351: h4984. PMID: 26432468, PMCID: PMC4591503, DOI: 10.1136/bmj.h4984.Peer-Reviewed Original ResearchConceptsSerotonin-norepinephrine reuptake inhibitorsMultiple chronic conditionsSelective serotonin reuptake inhibitorsAdjusted hazard ratioRisk of deathCalcium channel blockersChronic conditionsHazard ratioΒ-blockersCohort studyReuptake inhibitorsAtrial fibrillationOlder adultsChannel blockersCardiovascular drugsSSRIs/serotonin-norepinephrine reuptake inhibitorsRenin-angiotensin system blockersNorepinephrine reuptake inhibitorsSerotonin reuptake inhibitorsCommon combinationRAS blockersSystem blockersStudy drugHeart failureThromboembolic disease
1999
Drugs and Falls in Older People: A Systematic Review and Meta‐analysis: II. Cardiac and Analgesic Drugs
Leipzig R, Cumming R, Tinetti M. Drugs and Falls in Older People: A Systematic Review and Meta‐analysis: II. Cardiac and Analgesic Drugs. Journal Of The American Geriatrics Society 1999, 47: 40-50. PMID: 9920228, DOI: 10.1111/j.1532-5415.1999.tb01899.x.Peer-Reviewed Original ResearchConceptsPooled odds ratioAnalgesic drugsOdds ratioDiuretic useRecurrent fallsOlder peopleOlder adultsAnalgesic drug useNonnarcotic analgesic useDuration of therapyIncidence of fallsNumber of fallersCalcium channel blockersMean subject ageEnglish-language articlesDigoxin useNSAID useAnalgesic useAspirin useLoop diureticsMedication useThiazide diureticsNarcotic useACE inhibitorsMore falls