2020
Clinical relevance of low-density Plasmodium falciparum parasitemia in untreated febrile children: A cohort study
Hartley M, Hofmann N, Keitel K, Kagoro F, Moniz C, Mlaganile T, Samaka J, Masimba J, Said Z, Temba H, Gonzalez I, Felger I, Genton B, D’Acremont V. Clinical relevance of low-density Plasmodium falciparum parasitemia in untreated febrile children: A cohort study. PLOS Medicine 2020, 17: e1003318. PMID: 32956354, PMCID: PMC7505590, DOI: 10.1371/journal.pmed.1003318.Peer-Reviewed Original ResearchConceptsFebrile childrenLD patientsSecondary hospitalizationCohort studyLD infectionLow-density Plasmodium infectionsMalaria rapid diagnostic testsFebrile pediatric outpatientsPlasmodium falciparum parasitemiaPrimary care levelClinical decision support algorithmPrimary care facilitiesRapid diagnostic testsHigh-density infectionsViral originPediatric outpatientsUndifferentiated feverClinical featuresClinical presentationHD patientsSevere malnutritionClinical benefitIncidental findingPlasmodium infectionPolymerase chain reaction
2017
Predicting Ebola infection: A malaria-sensitive triage score for Ebola virus disease
Hartley M, Young A, Tran A, Okoni-Williams H, Suma M, Mancuso B, Al-Dikhari A, Faouzi M. Predicting Ebola infection: A malaria-sensitive triage score for Ebola virus disease. PLOS Neglected Tropical Diseases 2017, 11: e0005356. PMID: 28231242, PMCID: PMC5322888, DOI: 10.1371/journal.pntd.0005356.Peer-Reviewed Original ResearchConceptsEbola virus diseaseEbola treatment centersEVD infectionTriage scoreDifferential diagnosisRetrospective cohort studyNon-specific symptomsImportant differential diagnosisPrevention/control measuresVirus diseaseCurrent triage protocolResource-poor settingsClinical characteristicsCohort studyEVD patientsUnivariate analysisNosocomial infectionsHigher oddsTriage toolPredictive scoreTreatment centersTriage protocolMultivariate analysisPatientsDifferential diagnostics