2024
PLUS-IS-LESS project: Procalcitonin and Lung UltraSonography-based antibiotherapy in patients with Lower rESpiratory tract infection in Swiss Emergency Departments: study protocol for a pragmatic stepped-wedge cluster-randomized trial
Bessat C, Bingisser R, Schwendinger M, Bulaty T, Fournier Y, Della Santa V, Pfeil M, Schwab D, Leuppi J, Geigy N, Steuer S, Roos F, Christ M, Sirova A, Espejo T, Riedel H, Atzl A, Napieralski F, Marti J, Cisco G, Foley R, Schindler M, Hartley M, Fayet A, Garcia E, Locatelli I, Albrich W, Hugli O, Boillat-Blanco N. PLUS-IS-LESS project: Procalcitonin and Lung UltraSonography-based antibiotherapy in patients with Lower rESpiratory tract infection in Swiss Emergency Departments: study protocol for a pragmatic stepped-wedge cluster-randomized trial. Trials 2024, 25: 86. PMID: 38273319, PMCID: PMC10809691, DOI: 10.1186/s13063-023-07795-y.Peer-Reviewed Original ResearchConceptsPrescription of antibioticsRespiratory tract infectionsLung ultrasoundSwiss emergency departmentEmergency departmentTract infectionsAntibiotic prescriptionsProportion of patients prescribed antibioticsBackgroundLower respiratory tract infectionsCluster-randomizedSide effectsAntibiotic-related side effectsLower respiratory tract infectionsLength of hospital stayPatients prescribed antibioticsClinical severity scoreClinical prediction scoreProportion of patientsReducing antibiotic prescriptionsCo-primary endpointsChest X-rayDecrease side effectsPreserving patient safetyPattern of pneumoniaProportion of antibiotics
2023
Barriers and facilitators to implementation of point-of-care lung ultrasonography in a tertiary centre in Benin: a qualitative study among general physicians and pneumologists
Suttels V, Da Costa S, Garcia E, Brahier T, Hartley M, Agodokpessi G, Wachinou P, Fasseur F, Boillat-Blanco N. Barriers and facilitators to implementation of point-of-care lung ultrasonography in a tertiary centre in Benin: a qualitative study among general physicians and pneumologists. BMJ Open 2023, 13: e070765. PMID: 37369423, PMCID: PMC10357755, DOI: 10.1136/bmjopen-2022-070765.Peer-Reviewed Original ResearchConceptsLower respiratory tract infectionsTertiary centerGeneral physiciansDiagnostic performanceProspective cohort studyRespiratory tract infectionsCare lung ultrasoundCare lung ultrasonographyProgram 6 monthsExcellent diagnostic performanceCohort studyImplementation of pointRespiratory symptomsTract infectionsMiddle-income countriesSpecialist careLung ultrasonographyLung ultrasoundPhysicians' perceptionsHospital settingPatient experienceQualitative studyDiagnostic approachClinical routineHealth equity
2020
Lung Ultrasonography for Risk Stratification in Patients with Coronavirus Disease 2019 (COVID-19): A Prospective Observational Cohort Study
Brahier T, Meuwly J, Pantet O, Vez M, Donnet H, Hartley M, Hugli O, Boillat-Blanco N. Lung Ultrasonography for Risk Stratification in Patients with Coronavirus Disease 2019 (COVID-19): A Prospective Observational Cohort Study. Clinical Infectious Diseases 2020, 73: e4189-e4196. PMID: 32940646, PMCID: PMC7543331, DOI: 10.1093/cid/ciaa1408.Peer-Reviewed Original ResearchConceptsLung ultrasonographyCoronavirus disease 2019Emergency departmentLUS scoreRisk stratificationDisease 2019Lower respiratory tract infectionsProspective observational cohort studyPleural line irregularitiesEarly risk stratificationObservational cohort studyProspective observational studyRespiratory tract infectionsRisk stratification toolConfluent B-linesDifferent clinical outcomesLausanne University HospitalCOVID-19B-linesLUS characteristicsLUS findingsCohort studyTract infectionsClinical outcomesPatient group