Featured Publications
The indelible toll of enteric pathogens: Prevalence, clinical characterization, and seasonal trends in patients with acute community-acquired diarrhea in disenfranchised communities
Osman M, Kassem I, Dabboussi F, Cummings K, Hamze M. The indelible toll of enteric pathogens: Prevalence, clinical characterization, and seasonal trends in patients with acute community-acquired diarrhea in disenfranchised communities. PLOS ONE 2023, 18: e0282844. PMID: 36913372, PMCID: PMC10010529, DOI: 10.1371/journal.pone.0282844.Peer-Reviewed Original ResearchConceptsEnteropathogenic E. coliEnteroaggregative Escherichia coliEnterotoxigenic E. coliEnteric pathogensCross-sectional community-based studyAcute community-acquired diarrheaMultivariable logistic regression modelCommon parasitic agentsCommunity-acquired diarrheaCommunity-based studyPublic health challengeLogistic regression modelsGII infectionsAcute diarrheaMiddle-income countriesGastrointestinal PanelDiarrheic patientsEnteric infectionsOverall prevalenceRisk factorsStool samplesClinical characterizationETEC infectionDiarrheal diseaseEtiologic agent
2019
First report on the prevalence and subtype distribution of Blastocystis sp. in dairy cattle in Lebanon and assessment of zoonotic transmission
Greige S, El Safadi D, Khaled S, Gantois N, Baydoun M, Chemaly M, Benamrouz-Vanneste S, Chabé M, Osman M, Certad G, Hamze M, Viscogliosi E. First report on the prevalence and subtype distribution of Blastocystis sp. in dairy cattle in Lebanon and assessment of zoonotic transmission. Acta Tropica 2019, 194: 23-29. PMID: 30878470, DOI: 10.1016/j.actatropica.2019.02.013.Peer-Reviewed Original ResearchConceptsDomestic cattleBlastocystis spCattle livestockDairy cattleFecal samplesLow host specificityNon-human hostsDairy farmersZoonotic potentialZoonotic transmissionCattleZoonotic reservoirsFarmers' CohortLivestockAnimal hostsST3 isolatesPossible reservoirST distributionHost specificityST10FarmsHuman populationHuman infectionsPositive samplesST1
2017
Prevalence, transmission, and host specificity of Cryptosporidium spp. in various animal groups from two French zoos
Osman M, El Safadi D, Benamrouz-Vanneste S, Cian A, Moriniere R, Gantois N, Delgado-Viscogliosi P, Guyot K, Bosc S, Chabé M, Petit T, Viscogliosi E, Certad G. Prevalence, transmission, and host specificity of Cryptosporidium spp. in various animal groups from two French zoos. Parasitology Research 2017, 116: 3419-3422. PMID: 29030716, DOI: 10.1007/s00436-017-5645-1.Peer-Reviewed Original ResearchConceptsCryptosporidium sppCaptivity animalsFrench zoosSpecies of CryptosporidiumPrevalence of CryptosporidiumFecal samplesC. galliC. tyzzeriC. andersoniCryptosporidium speciesFirst molecular studyCryptosporidium DNACryptosporidium infectionHost specificityPotential reservoirsDifferent hostsCryptosporidiumMolecular studiesZoological gardensSpeciesAnimal groupsSppAnimalsParasitesAndersoni
2016
Prevalence and Risk Factors for Intestinal Protozoan Infections with Cryptosporidium, Giardia, Blastocystis and Dientamoeba among Schoolchildren in Tripoli, Lebanon
Osman M, Safadi D, Cian A, Benamrouz S, Nourrisson C, Poirier P, Pereira B, Razakandrainibe R, Pinon A, Lambert C, Wawrzyniak I, Dabboussi F, Delbac F, Favennec L, Hamze M, Viscogliosi E, Certad G. Prevalence and Risk Factors for Intestinal Protozoan Infections with Cryptosporidium, Giardia, Blastocystis and Dientamoeba among Schoolchildren in Tripoli, Lebanon. PLOS Neglected Tropical Diseases 2016, 10: e0004496. PMID: 26974335, PMCID: PMC4790957, DOI: 10.1371/journal.pntd.0004496.Peer-Reviewed Original ResearchConceptsIntestinal protozoan infectionsProtozoan infectionsRisk factorsAssemblages of GiardiaGeneral pediatric populationPrimary risk factorCross-sectional studyPersonal hygiene habitsIntestinal pathogenic protozoaMolecular epidemiological dataLogistic regression modelsHigher infection rateSubtypes of BlastocystisDigestive symptomsPediatric populationGastrointestinal disordersAsymptomatic infectionAsymptomatic subjectsHygiene habitsOverall prevalenceStool samplesHigh prevalenceEpidemiological dataHigh riskDientamoeba fragilis
2015
Initial Data on the Molecular Epidemiology of Cryptosporidiosis in Lebanon
Osman M, Safadi D, Benamrouz S, Guyot K, Dei-Cas E, Aliouat E, Creusy C, Mallat H, Hamze M, Dabboussi F, Viscogliosi E, Certad G. Initial Data on the Molecular Epidemiology of Cryptosporidiosis in Lebanon. PLOS ONE 2015, 10: e0125129. PMID: 25950832, PMCID: PMC4423932, DOI: 10.1371/journal.pone.0125129.Peer-Reviewed Original ResearchConceptsMajor public health problemPublic health problemZiehl-Neelsen stainingCryptosporidium sppC. parvum subtypesGastrointestinal disordersRare subtypeImmunocompromised personsOverall prevalenceGastrointestinal tractHealth problemsFecal specimensMolecular epidemiologyEpidemiologyC. parvumPositive samplesPatientsHigh rateC. hominisInfectionPrevalenceSubtypesGp60 locusNorth LebanonCryptosporidiumAcute Blastocystis-Associated Appendicular Peritonitis in a Child, Casablanca, Morocco - Volume 21, Number 1—January 2015 - Emerging Infectious Diseases journal - CDC
Fréalle E, Safadi D, Cian A, Aubry E, Certad G, Osman M, Wacrenier A, Dutoit E, Creusy C, Dubos F, Viscogliosi E. Acute Blastocystis-Associated Appendicular Peritonitis in a Child, Casablanca, Morocco - Volume 21, Number 1—January 2015 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2015, 21: 91-94. PMID: 25528951, PMCID: PMC4285265, DOI: 10.3201/eid2101.140544.Peer-Reviewed Original Research
2013
Molecular Epidemiology of Blastocystis in Lebanon and Correlation between Subtype 1 and Gastrointestinal Symptoms
Safadi D, Meloni D, Poirier P, Osman M, Cian A, Gaayeb L, Wawrzyniak I, Delbac F, Alaoui H, Delhaes L, Dei-Cas E, Mallat H, Dabboussi F, Hamze M, Viscogliosi E. Molecular Epidemiology of Blastocystis in Lebanon and Correlation between Subtype 1 and Gastrointestinal Symptoms. American Journal Of Tropical Medicine And Hygiene 2013, 88: 1203-1206. PMID: 23458955, PMCID: PMC3752823, DOI: 10.4269/ajtmh.12-0777.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBlastocystisBlastocystis InfectionsChildChild, PreschoolDNA, ProtozoanFecesFemaleGastrointestinal TractGenotypeHumansInfantLebanonMaleMiddle AgedMolecular EpidemiologyPrevalenceRibosome Subunits, SmallSequence Analysis, DNASpecimen HandlingYoung AdultConceptsLebanese populationCommon eukaryotic parasiteRibosomal RNA gene sequencingRNA gene sequencingAsymptomatic patientsGastrointestinal symptomsSymptomatic patientsSubtype 1Intestinal tractMolecular epidemiologyPatientsBlastocystis subtypesDirect light microscopyFecal samplesPublic healthSubtypesST distributionBlastocystis isolatesBlastocystisGene sequencingParasitesPopulationST1SymptomsEpidemiology