Featured Publications
The indelible toll of enteric pathogens: Prevalence, clinical characterization, and seasonal trends in patients with acute community-acquired diarrhea in disenfranchised communities
Osman M, Kassem I, Dabboussi F, Cummings K, Hamze M. The indelible toll of enteric pathogens: Prevalence, clinical characterization, and seasonal trends in patients with acute community-acquired diarrhea in disenfranchised communities. PLOS ONE 2023, 18: e0282844. PMID: 36913372, PMCID: PMC10010529, DOI: 10.1371/journal.pone.0282844.Peer-Reviewed Original ResearchConceptsEnteropathogenic E. coliEnteroaggregative Escherichia coliEnterotoxigenic E. coliEnteric pathogensCross-sectional community-based studyAcute community-acquired diarrheaMultivariable logistic regression modelCommon parasitic agentsCommunity-acquired diarrheaCommunity-based studyPublic health challengeLogistic regression modelsGII infectionsAcute diarrheaMiddle-income countriesGastrointestinal PanelDiarrheic patientsEnteric infectionsOverall prevalenceRisk factorsStool samplesClinical characterizationETEC infectionDiarrheal diseaseEtiologic agent
2017
High association of Cryptosporidium spp. infection with colon adenocarcinoma in Lebanese patients
Osman M, Benamrouz S, Guyot K, Baydoun M, Frealle E, Chabe M, Gantois N, Delaire B, Goffard A, Aoun A, Jurdi N, Dabboussi F, Even G, Slomianny C, Gosset P, Hamze M, Creusy C, Viscogliosi E, Certad G. High association of Cryptosporidium spp. infection with colon adenocarcinoma in Lebanese patients. PLOS ONE 2017, 12: e0189422. PMID: 29261714, PMCID: PMC5736188, DOI: 10.1371/journal.pone.0189422.Peer-Reviewed Original ResearchConceptsGroup of patientsLebanese patientsHuman colon cancerColon cancerColon adenocarcinomaPersistent digestive symptomsPersistent gastrointestinal symptomsRisk of infectionPotential etiological agentsPrevalence of CryptosporidiumDigestive symptomsGastrointestinal symptomsNormal biopsiesDigestive cancersColon neoplasiaDigestive biopsiesPatientsAdenocarcinomaBiopsyCancerPrevalenceEtiological agentHigh associationHuman cancersCryptosporidium prevalencePrevalence, transmission, and host specificity of Cryptosporidium spp. in various animal groups from two French zoos
Osman M, El Safadi D, Benamrouz-Vanneste S, Cian A, Moriniere R, Gantois N, Delgado-Viscogliosi P, Guyot K, Bosc S, Chabé M, Petit T, Viscogliosi E, Certad G. Prevalence, transmission, and host specificity of Cryptosporidium spp. in various animal groups from two French zoos. Parasitology Research 2017, 116: 3419-3422. PMID: 29030716, DOI: 10.1007/s00436-017-5645-1.Peer-Reviewed Original ResearchConceptsCryptosporidium sppCaptivity animalsFrench zoosSpecies of CryptosporidiumPrevalence of CryptosporidiumFecal samplesC. galliC. tyzzeriC. andersoniCryptosporidium speciesFirst molecular studyCryptosporidium DNACryptosporidium infectionHost specificityPotential reservoirsDifferent hostsCryptosporidiumMolecular studiesZoological gardensSpeciesAnimal groupsSppAnimalsParasitesAndersoni
2015
Prevalence and genetic diversity of the intestinal parasites Blastocystis sp. and Cryptosporidium spp. in household dogs in France and evaluation of zoonotic transmission risk
Osman M, Bories J, Safadi D, Poirel M, Gantois N, Benamrouz-Vanneste S, Delhaes L, Hugonnard M, Certad G, Zenner L, Viscogliosi E. Prevalence and genetic diversity of the intestinal parasites Blastocystis sp. and Cryptosporidium spp. in household dogs in France and evaluation of zoonotic transmission risk. Veterinary Parasitology 2015, 214: 167-170. PMID: 26395822, DOI: 10.1016/j.vetpar.2015.09.015.Peer-Reviewed Original ResearchConceptsCryptosporidium sppHousehold dogsBlastocystis spC. canisCanine populationZoonotic transmission riskFecal samplesZoonotic riskGastrointestinal parasitesDomestic dogsZoonotic reservoirsGenetic diversityCystoisospora spGastrointestinal symptomsCommon parasiteLight microscopy examinationNatural hostOverall prevalenceSppLow prevalenceSubtype 2Giardia spIntestinal parasitesIntestinal protozoaMolecular epidemiologyIdentification of Cryptosporidium Species in Fish from Lake Geneva (Lac Léman) in France
Certad G, Dupouy-Camet J, Gantois N, Hammouma-Ghelboun O, Pottier M, Guyot K, Benamrouz S, Osman M, Delaire B, Creusy C, Viscogliosi E, Dei-Cas E, Aliouat-Denis C, Follet J. Identification of Cryptosporidium Species in Fish from Lake Geneva (Lac Léman) in France. PLOS ONE 2015, 10: e0133047. PMID: 26213992, PMCID: PMC4516323, DOI: 10.1371/journal.pone.0133047.Peer-Reviewed Original ResearchConceptsC. molnariC. parvumCryptosporidium speciesEdible freshwater fishDigestive epithelial cellsFreshwater fishZoonotic speciesCryptosporidium sppCryptosporidium subtypesWildlife speciesGp60 subtypesFish speciesTerrestrial mammalsCoregonus lavaretusDegenerate primersEntire fishPotential hostsSequence analysisPerca fluviatilisRutilus rutilusSalvelinus alpinusEsox luciusDevelopmental stagesParvumLake GenevaInitial Data on the Molecular Epidemiology of Cryptosporidiosis in Lebanon
Osman M, Safadi D, Benamrouz S, Guyot K, Dei-Cas E, Aliouat E, Creusy C, Mallat H, Hamze M, Dabboussi F, Viscogliosi E, Certad G. Initial Data on the Molecular Epidemiology of Cryptosporidiosis in Lebanon. PLOS ONE 2015, 10: e0125129. PMID: 25950832, PMCID: PMC4423932, DOI: 10.1371/journal.pone.0125129.Peer-Reviewed Original ResearchConceptsMajor public health problemPublic health problemZiehl-Neelsen stainingCryptosporidium sppC. parvum subtypesGastrointestinal disordersRare subtypeImmunocompromised personsOverall prevalenceGastrointestinal tractHealth problemsFecal specimensMolecular epidemiologyEpidemiologyC. parvumPositive samplesPatientsHigh rateC. hominisInfectionPrevalenceSubtypesGp60 locusNorth LebanonCryptosporidium