2020
Endocannabinoids Attenuate the Virulence of Certain Enteropathogenic Bacteria
Osman M, Papon N, Weill F. Endocannabinoids Attenuate the Virulence of Certain Enteropathogenic Bacteria. Trends In Microbiology 2020, 29: 185-187. PMID: 33388214, DOI: 10.1016/j.tim.2020.12.008.Peer-Reviewed Original ResearchConceptsEndocannabinoid systemInflammatory bowel diseaseIntestinal bacterial infectionsMammalian endocannabinoid systemBowel diseaseEnteric infectionsIntestinal infectionsLipid hormonesGastrointestinal physiologyBacterial infectionsEnteropathogenic bacteriaInfectionPromising targetPossible benefitsNew findingsDiseaseMiceHormoneImmunityCannabinoids
2014
Cryptosporidium parvum-induced ileo-caecal adenocarcinoma and Wnt signaling in a mouse model
Benamrouz S, Conseil V, Chabé M, Praet M, Audebert C, Blervaque R, Guyot K, Gazzola S, Mouray A, Chassat T, Delaire B, Goetinck N, Gantois N, Osman M, Slomianny C, Dehennaut V, Lefebvre T, Viscogliosi E, Cuvelier C, Dei-Cas E, Creusy C, Certad G. Cryptosporidium parvum-induced ileo-caecal adenocarcinoma and Wnt signaling in a mouse model. Disease Models & Mechanisms 2014, 7: 693-700. PMID: 24652769, PMCID: PMC4036476, DOI: 10.1242/dmm.013292.Peer-Reviewed Original ResearchConceptsHost cell biological processesCell migrationHigh-throughput sequencingHost-pathogen interactionsPotential tumorigenic roleCytoskeleton activityAnimal modelsAdherens junctionsCytoskeleton networkC. parvum-infected micePathway componentsBiological processesApicomplexan protozoaCell cycleStudied genesInfection processMetabolic pathwaysSelf-limiting diarrheaReproducible animal modelC. parvumAdult SCID miceLife-threatening diseaseΒ-cateninTumorigenic roleCryptosporidium species