2020
Investigation of an XDR-Acinetobacter baumannii ST2 outbreak in an intensive care unit of a Lebanese tertiary care hospital
Osman M, Halimeh F, Rafei R, Mallat H, Tom J, Raad E, Diene S, Jamal S, Al Atrouni A, Dabboussi F, Moudani W, Madec J, Saras E, Lupo A, Haenni M, Rolain J, Hamze M. Investigation of an XDR-Acinetobacter baumannii ST2 outbreak in an intensive care unit of a Lebanese tertiary care hospital. Future Microbiology 2020, 15: 1535-1542. PMID: 33215520, DOI: 10.2217/fmb-2020-0079.Peer-Reviewed Original ResearchMeSH KeywordsAcinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsBacterial ProteinsBeta-LactamasesCarbapenemsCross InfectionDisease OutbreaksDrug Resistance, Multiple, BacterialFemaleHumansIntensive Care UnitsLebanonMaleMicrobial Sensitivity TestsMiddle AgedPhylogenyTertiary Care CentersConceptsTertiary care hospitalCare hospitalPolymerase chain reactionInfection preventionPulsed-field gel electrophoresisAppropriate infection preventionIntensive care unitReal-time polymerase chain reactionMultilocus sequence typing analysisHospitalized patientsCare unitPolyclonal outbreakOXA-23Epidemiological relatednessSequence typing analysisControl measuresHospitalChain reactionFull eradicationTyping analysisPreventionOutbreakGel electrophoresisPatients
2018
Epidemiology of antimicrobial resistance in Lebanese extra-hospital settings: An overview
Osman M, Al Mir H, Rafei R, Dabboussi F, Madec J, Haenni M, Hamze M. Epidemiology of antimicrobial resistance in Lebanese extra-hospital settings: An overview. Journal Of Global Antimicrobial Resistance 2018, 17: 123-129. PMID: 30553113, DOI: 10.1016/j.jgar.2018.11.019.Peer-Reviewed Original ResearchConceptsAntimicrobial resistanceExtra-hospital settingsTerms of mortalityMiracle drugAntimicrobial-resistant pathogensNon-clinical settingsSignificant morbidityClinical settingNovel drugsAntimicrobial-resistant bacteriaMultidrug-resistant bacterial strainsSocietal costsInappropriate useCombat infectionEpidemiological situationMorbidityMortalityEpidemiologyDrugsAntibioticsVeterinary medicineAMR crisisMajority of investigations
2017
Prevalence, antibiotic susceptibility and characterization of antibiotic resistant genes among carbapenem-resistant Gram-negative bacilli and yeast in intestinal flora of cancer patients in North Lebanon
Christophy R, Osman M, Mallat H, Achkar M, Ziedeh A, Moukaddem W, Dabboussi F, Hamze M. Prevalence, antibiotic susceptibility and characterization of antibiotic resistant genes among carbapenem-resistant Gram-negative bacilli and yeast in intestinal flora of cancer patients in North Lebanon. Journal Of Infection And Public Health 2017, 10: 716-720. PMID: 28216021, DOI: 10.1016/j.jiph.2016.10.009.Peer-Reviewed Original ResearchConceptsCarbapenem-resistant bacteriaCancer patientsIntestinal carriageCarbapenem-resistant Gram-negative bacilliAntibiotic stewardship programsInfection control measuresDepartment of ChemotherapyGram-negative bacilliOXA-48 genePublic health concernAntimicrobial susceptibility profilesNini HospitalEndogenous infectionsMechanisms of resistanceStool samplesHigh prevalenceIntestinal floraHodge testStewardship programsPatientsAntibiotic susceptibilityNorth LebanonChemotherapySusceptibility profilesHealth concern