2021
Cl415, a carbapenem-resistant Acinetobacter baumannii isolate containing four AbaR4 and a new variant of AbGRI2, represents a novel global clone 2 strain
Liepa R, Mann R, Osman M, Hamze M, Gunawan C, Hamidian M. Cl415, a carbapenem-resistant Acinetobacter baumannii isolate containing four AbaR4 and a new variant of AbGRI2, represents a novel global clone 2 strain. Journal Of Antimicrobial Chemotherapy 2021, 77: 345-350. PMID: 34741594, PMCID: PMC8809195, DOI: 10.1093/jac/dkab399.Peer-Reviewed Original ResearchConceptsWhole genome sequencesWide geographical distributionGene complementNovel variantsPhylogenetic analysisGenomic analysisNew lineageComplete genomeOxford NanoporeIllumina MiSeqGenetic contextResistance genesGenesAntibiotic resistance determinantsResistance phenotypeGeographical distributionCopiesAntibiotic resistance phenotypesResistance islandsGlobal distributionResistance determinantsComM geneAntibiotic resistanceSubcladesVariants
2018
Diversity and Evolution of Sensor Histidine Kinases in Eukaryotes
Kabbara S, Hérivaux A, de Bernonville T, Courdavault V, Clastre M, Gastebois A, Osman M, Hamze M, Cock J, Schaap P, Papon N. Diversity and Evolution of Sensor Histidine Kinases in Eukaryotes. Genome Biology And Evolution 2018, 11: 86-108. PMID: 30252070, PMCID: PMC6324907, DOI: 10.1093/gbe/evy213.Peer-Reviewed Original ResearchConceptsTwo-component systemHistidine kinaseHK proteinsEukaryotic supergroupsPhylogenetic analysisMajor eukaryotic supergroupsSensor histidine kinaseIndependent phylogenetic analysesEukaryotic speciesGenomic resourcesEukaryotic organismsPhylogenetic distributionPhylogenetic lineagesPhysiological traitsPhylogenetic treeHK genesSensor proteinsTransduction systemEnvironmental cuesUnprecedented overviewSingle kingdomEukaryotesProteinStructural diversityEvolutionary path