2022
Prevalence and Molecular Mechanisms of Carbapenem Resistance among Gram-Negative Bacilli in Three Hospitals of Northern Lebanon
Rima M, Oueslati S, Dabos L, Daaboul D, Mallat H, Raad E, Achkar M, Mawlawi O, Bernabeu S, Bonnin R, Girlich D, Osman M, Hamze M, Naas T. Prevalence and Molecular Mechanisms of Carbapenem Resistance among Gram-Negative Bacilli in Three Hospitals of Northern Lebanon. Antibiotics 2022, 11: 1295. PMID: 36289953, PMCID: PMC9598570, DOI: 10.3390/antibiotics11101295.Peer-Reviewed Original ResearchCarbapenem-resistant Gram-negative bacilliCarbapenem resistanceGram-negative bacilliHealth care centersCare centerEpidemiological surveyDiscordant resultsCarba NP testHealth issuesOXA-162PCR sequencingNP testHospitalPrevalenceMolecular mechanismsNovel variantsIsolatesImmunochromatographic assayRegistration systemResistance spreadOXABacilliCarbapenemsGenes
2018
Molecular mechanisms of antimicrobial resistance in Acinetobacter baumannii, with a special focus on its epidemiology in Lebanon
Jamal S, Al Atrouni A, Rafei R, Dabboussi F, Hamze M, Osman M. Molecular mechanisms of antimicrobial resistance in Acinetobacter baumannii, with a special focus on its epidemiology in Lebanon. Journal Of Global Antimicrobial Resistance 2018, 15: 154-163. PMID: 29859266, DOI: 10.1016/j.jgar.2018.05.022.Peer-Reviewed Original ResearchConceptsAcinetobacter baumanniiA. baumannii outbreaksIntensive care unitAntimicrobial resistanceType of infectionInternational clones ICare unitA. baumanniiHigh mortalityMolecular epidemiologyOpportunistic bacteriumBaumanniiWorldwide emergenceInfectionEpidemiologySpecific clonesMolecular mechanismsClone IMorbidityMolecular techniquesSpecial focusMortalityAvailable data
2017
Molecular mechanisms and epidemiology of resistance in Streptococcus pneumoniae in the Middle East region
El Moujaber G, Osman M, Rafei R, Dabboussi F, Hamze M. Molecular mechanisms and epidemiology of resistance in Streptococcus pneumoniae in the Middle East region. Journal Of Medical Microbiology 2017, 66: 847-858. PMID: 28650313, DOI: 10.1099/jmm.0.000503.Peer-Reviewed Original ResearchConceptsS. pneumoniaeStreptococcus pneumoniaeDrug-resistant S. pneumoniaeAcute otitis mediaNon-invasive infectionsEmergence of multidrugEpidemiology of resistanceS. pneumoniae strainsPrevalence of resistanceMiddle Eastern countriesMolecular mechanismsOtitis mediaMechanisms of resistanceNational surveillanceAntimicrobial stewardshipEastern countriesPneumococcal strainsPneumoniae strainsHigh mortalityNasopharyngeal cavityDecreased susceptibilityCommensal bacteriumSurveillance reportsPneumoniaeAntimicrobial resistance