2023
Identification of genes influencing the evolution of Escherichia coli ST372 in dogs and humans
Elankumuran P, Browning G, Marenda M, Kidsley A, Osman M, Haenni M, Johnson J, Trott D, Reid C, Djordjevic S. Identification of genes influencing the evolution of Escherichia coli ST372 in dogs and humans. Microbial Genomics 2023, 9: mgen000930. PMID: 36752777, PMCID: PMC9997745, DOI: 10.1099/mgen.0.000930.Peer-Reviewed Original ResearchConceptsPopulation structureIdentification of genesWhole genome sequencesPropanediol utilization (pdu) operonGenomic traitsAccessory genomeCanine sourcesBioinformatics analysisUtilization operonPhylogenetic clustersGlobal collectionDistinct populationsVirulence genesOperonGenesDominant hostSequence typesSequenceExtraintestinal infectionsPhylogenyCladeGenomeLineagesHumansTraits
2015
Pathogenesis of Cryptosporidium in Humans
Certad G, Osman M, Benamrouz S. Pathogenesis of Cryptosporidium in Humans. 2015, 371-391. DOI: 10.1002/9781118644843.ch20.Peer-Reviewed Original ResearchCryptosporidium infectionT cell-deficient miceModulation of apoptosisT cellsImmune responseAthymic miceResistant oocystsPrecise diagnosisBarrier functionTight cell junctionsInfectionCellular damageSusceptible hostsMiceCryptosporidiumMolecular characterizationCell junctionsHumansPathogenesisEpidemiologyDiseaseDiagnosisIngestion