2024
Neonatal sepsis due to NDM-1 and VIM-2 co-producing Pseudomonas aeruginosa in Morocco
Daaboul D, Osman M, Kassem I, Yassine I, Girlich D, Proust A, Mounir C, Zerouali K, Raymond J, Naas T, Oueslati S. Neonatal sepsis due to NDM-1 and VIM-2 co-producing Pseudomonas aeruginosa in Morocco. Journal Of Antimicrobial Chemotherapy 2024, 79: 1614-1618. PMID: 38804143, DOI: 10.1093/jac/dkae153.Peer-Reviewed Original ResearchNeonatal intensive care unitBlaVIM-2BlaNDM-1Intensive care unitCenter of Genomic EpidemiologyBlaVIM-2 geneIntegrative conjugative elementsWhole-genome sequencingAntimicrobial resistance genesBlaNDM-1 geneAntimicrobial susceptibility testingCarbapenem-resistant Pseudomonas aeruginosaCare unitLast-resort antibioticsSusceptible to colistinResistance to cefiderocolXDR P. aeruginosaGram-negative bacteriaCarba NPMetallo-b-lactamasesReducing treatment optionsConjugative elementsSequence typingESBL genesMinION technology
2020
Investigation of an XDR-Acinetobacter baumannii ST2 outbreak in an intensive care unit of a Lebanese tertiary care hospital
Osman M, Halimeh F, Rafei R, Mallat H, Tom J, Raad E, Diene S, Jamal S, Al Atrouni A, Dabboussi F, Moudani W, Madec J, Saras E, Lupo A, Haenni M, Rolain J, Hamze M. Investigation of an XDR-Acinetobacter baumannii ST2 outbreak in an intensive care unit of a Lebanese tertiary care hospital. Future Microbiology 2020, 15: 1535-1542. PMID: 33215520, DOI: 10.2217/fmb-2020-0079.Peer-Reviewed Original ResearchMeSH KeywordsAcinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsBacterial ProteinsBeta-LactamasesCarbapenemsCross InfectionDisease OutbreaksDrug Resistance, Multiple, BacterialFemaleHumansIntensive Care UnitsLebanonMaleMicrobial Sensitivity TestsMiddle AgedPhylogenyTertiary Care CentersConceptsTertiary care hospitalCare hospitalPolymerase chain reactionInfection preventionPulsed-field gel electrophoresisAppropriate infection preventionIntensive care unitReal-time polymerase chain reactionMultilocus sequence typing analysisHospitalized patientsCare unitPolyclonal outbreakOXA-23Epidemiological relatednessSequence typing analysisControl measuresHospitalChain reactionFull eradicationTyping analysisPreventionOutbreakGel electrophoresisPatients
2018
Molecular mechanisms of antimicrobial resistance in Acinetobacter baumannii, with a special focus on its epidemiology in Lebanon
Jamal S, Al Atrouni A, Rafei R, Dabboussi F, Hamze M, Osman M. Molecular mechanisms of antimicrobial resistance in Acinetobacter baumannii, with a special focus on its epidemiology in Lebanon. Journal Of Global Antimicrobial Resistance 2018, 15: 154-163. PMID: 29859266, DOI: 10.1016/j.jgar.2018.05.022.Peer-Reviewed Original ResearchConceptsAcinetobacter baumanniiA. baumannii outbreaksIntensive care unitAntimicrobial resistanceType of infectionInternational clones ICare unitA. baumanniiHigh mortalityMolecular epidemiologyOpportunistic bacteriumBaumanniiWorldwide emergenceInfectionEpidemiologySpecific clonesMolecular mechanismsClone IMorbidityMolecular techniquesSpecial focusMortalityAvailable data