2018
Molecular epidemiology of Cryptosporidium spp. in North Lebanon.
Osman M, Benamrouz S, Guyot K, El Safadi D, Mallat H, Dabboussi F, Hamze M, Viscogliosi E, Certad G. Molecular epidemiology of Cryptosporidium spp. in North Lebanon. The Journal Of Infection In Developing Countries 2018, 12: 34s. PMID: 31805009, DOI: 10.3855/jidc.10014.Peer-Reviewed Original ResearchRisk factorsFirst molecular epidemiology studySymptomatic hospitalized patientsIntestinal parasitic infectionsZiehl-Neelsen stainingMain transmission routeCryptosporidium sppMolecular epidemiology studiesGastrointestinal symptomsHospitalized patientsGastrointestinal tractParasitic infectionsEpidemiology studiesNorth LebanonPredominant causeMolecular epidemiologyChild populationFoodborne outbreaksMolecular testsCryptosporidiosisSocio-economic levelEpidemiological situationTransmission routesC. parvumFecal samples
2015
Identification of Cryptosporidium Species in Fish from Lake Geneva (Lac Léman) in France
Certad G, Dupouy-Camet J, Gantois N, Hammouma-Ghelboun O, Pottier M, Guyot K, Benamrouz S, Osman M, Delaire B, Creusy C, Viscogliosi E, Dei-Cas E, Aliouat-Denis C, Follet J. Identification of Cryptosporidium Species in Fish from Lake Geneva (Lac Léman) in France. PLOS ONE 2015, 10: e0133047. PMID: 26213992, PMCID: PMC4516323, DOI: 10.1371/journal.pone.0133047.Peer-Reviewed Original ResearchConceptsC. molnariC. parvumCryptosporidium speciesEdible freshwater fishDigestive epithelial cellsFreshwater fishZoonotic speciesCryptosporidium sppCryptosporidium subtypesWildlife speciesGp60 subtypesFish speciesTerrestrial mammalsCoregonus lavaretusDegenerate primersEntire fishPotential hostsSequence analysisPerca fluviatilisRutilus rutilusSalvelinus alpinusEsox luciusDevelopmental stagesParvumLake GenevaInitial Data on the Molecular Epidemiology of Cryptosporidiosis in Lebanon
Osman M, Safadi D, Benamrouz S, Guyot K, Dei-Cas E, Aliouat E, Creusy C, Mallat H, Hamze M, Dabboussi F, Viscogliosi E, Certad G. Initial Data on the Molecular Epidemiology of Cryptosporidiosis in Lebanon. PLOS ONE 2015, 10: e0125129. PMID: 25950832, PMCID: PMC4423932, DOI: 10.1371/journal.pone.0125129.Peer-Reviewed Original ResearchConceptsMajor public health problemPublic health problemZiehl-Neelsen stainingCryptosporidium sppC. parvum subtypesGastrointestinal disordersRare subtypeImmunocompromised personsOverall prevalenceGastrointestinal tractHealth problemsFecal specimensMolecular epidemiologyEpidemiologyC. parvumPositive samplesPatientsHigh rateC. hominisInfectionPrevalenceSubtypesGp60 locusNorth LebanonCryptosporidium
2014
Cryptosporidium parvum-induced ileo-caecal adenocarcinoma and Wnt signaling in a mouse model
Benamrouz S, Conseil V, Chabé M, Praet M, Audebert C, Blervaque R, Guyot K, Gazzola S, Mouray A, Chassat T, Delaire B, Goetinck N, Gantois N, Osman M, Slomianny C, Dehennaut V, Lefebvre T, Viscogliosi E, Cuvelier C, Dei-Cas E, Creusy C, Certad G. Cryptosporidium parvum-induced ileo-caecal adenocarcinoma and Wnt signaling in a mouse model. Disease Models & Mechanisms 2014, 7: 693-700. PMID: 24652769, PMCID: PMC4036476, DOI: 10.1242/dmm.013292.Peer-Reviewed Original ResearchConceptsHost cell biological processesCell migrationHigh-throughput sequencingHost-pathogen interactionsPotential tumorigenic roleCytoskeleton activityAnimal modelsAdherens junctionsCytoskeleton networkC. parvum-infected micePathway componentsBiological processesApicomplexan protozoaCell cycleStudied genesInfection processMetabolic pathwaysSelf-limiting diarrheaReproducible animal modelC. parvumAdult SCID miceLife-threatening diseaseΒ-cateninTumorigenic roleCryptosporidium species