The genetics of left-right development and heterotaxia
Bowers P, Brueckner M, Yost H. The genetics of left-right development and heterotaxia. Seminars In Perinatology 1996, 20: 577-588. PMID: 9090782, DOI: 10.1016/s0146-0005(96)80070-x.Peer-Reviewed Original ResearchConceptsLeft-right developmentMolecular genetic mechanismsPrimitive heart tubeSingle geneCardiac morphogenesisDifferent genesCardiac loopingHeart tubeGenesPhenotypeComplex groupHeterotaxiaMorphogenesisMost crucial stepCrucial stepGeneticsElucidationLoopingWide spectrumDevelopment resultsCongenital heartLaterality disturbances
Bowers P, Brueckner M, Yost H. Laterality disturbances. Progress In Pediatric Cardiology 1996, 6: 53-62. DOI: 10.1016/1058-9813(96)00171-3.Peer-Reviewed Original ResearchLeft-right body axisBody axisEmbryonic left-right axisPrimitive heart tubeLeft-right axisLeft-right asymmetryCardiac morphogenesisHeart developmentDevelopmental processesDorsoventral axesGenetic stepsHeart tubeMolecular levelLoop formationLaterality disturbancesComplex groupMorphogenesisFormation resultsVisible asymmetry