2004
The Novel Cdc42 Guanine Nucleotide Exchange Factor, Zizimin1, Dimerizes via the Cdc42-binding CZH2 Domain*
Meller N, Irani-Tehrani M, Ratnikov BI, Paschal BM, Schwartz MA. The Novel Cdc42 Guanine Nucleotide Exchange Factor, Zizimin1, Dimerizes via the Cdc42-binding CZH2 Domain*. Journal Of Biological Chemistry 2004, 279: 37470-37476. PMID: 15247287, DOI: 10.1074/jbc.m404535200.Peer-Reviewed Original ResearchConceptsExchange factorCdc42 Guanine Nucleotide Exchange FactorGuanine nucleotide exchange factorsRho family small GTPasesDomain-containing proteinsNucleotide exchange factorsMultiple cellular processesCDM proteinsCZH proteinsSmall GTPasesRho proteinsCellular processesCdc42 activationRho-GEFsCdc42Acid regionHomology analysisCritical regulatorZizimin1ProteinPositive cooperativityMutation analysisDimerizationDock180GTPases
1988
How actin binds and assembles onto plasma membranes from Dictyostelium discoideum.
Schwartz M, Luna E. How actin binds and assembles onto plasma membranes from Dictyostelium discoideum. Journal Of Cell Biology 1988, 107: 201-209. PMID: 3392099, PMCID: PMC2115166, DOI: 10.1083/jcb.107.1.201.Peer-Reviewed Original ResearchConceptsPolymerizationSuccessive monomersMembrane surfacePositive cooperativityActin trimerTight bindingAssembly stateHistidine-40Critical concentrationLow salt bufferDerivativesSalt bufferEthoxyformic anhydrideCooperativitySolutionMonomersMembraneAffinityMultivalencyOligomersAnhydrideActin nucleiBindingCross-linking experimentsActin oligomers