1996
Transformation by Rho exchange factor oncogenes is mediated by activation of an integrin‐dependent pathway.
Schwartz M, Toksoz D, Khosravi‐Far R. Transformation by Rho exchange factor oncogenes is mediated by activation of an integrin‐dependent pathway. The EMBO Journal 1996, 15: 6525-6530. PMID: 8978679, PMCID: PMC452477, DOI: 10.1002/j.1460-2075.1996.tb01043.x.Peer-Reviewed Original ResearchMeSH Keywords3T3 CellsA Kinase Anchor ProteinsAdaptor Proteins, Signal TransducingAnimalsCalciumCell DivisionCell Transformation, NeoplasticGTP-Binding ProteinsGuanine Nucleotide Exchange FactorsIntegrinsKineticsMiceMinor Histocompatibility AntigensModels, BiologicalOncogenesPhosphatidylinositol 4,5-DiphosphateProto-Oncogene ProteinsRetroviridae Proteins, OncogenicRho GTP-Binding ProteinsSignal TransductionThrombinConceptsConstitutive activationCell growthIntegrin signal transductionSmall GTPase RhoIntegrin-dependent pathwaySignal transductionSignaling eventsGrowth factor receptorGTPase RhoSerum-dependent growthAnchorage independenceFactor receptorPathwayOncogeneUncontrolled growthRhoActivationImportant mediatorTumor cellsGrowthTransductionTransmit signalDblGrowth resultsAnchorage
1992
Transmembrane signalling by integrins
Schwartz M. Transmembrane signalling by integrins. Trends In Cell Biology 1992, 2: 304-308. PMID: 14731926, DOI: 10.1016/0962-8924(92)90120-c.Peer-Reviewed Original Research
1990
Cytoplasmic pH and anchorage-independent growth induced by v-Ki-ras, v-src or polyoma middle T.
Schwartz M, Rupp E, Frangioni J, Lechene C. Cytoplasmic pH and anchorage-independent growth induced by v-Ki-ras, v-src or polyoma middle T. Oncogene 1990, 5: 55-8. PMID: 2181378.Peer-Reviewed Original ResearchConceptsAnchorage-independent growthNormal cellsCytoplasmic pHPolyoma middle T oncogeneRas-transformed cellsCell linesExtracellular matrix proteinsMiddle T oncogeneV-SrcSrc oncogeneTissue culture plasticMatrix proteinsCellular requirementsCell growthControl growthOncogeneV-KiAlkaline pHiSeries of cellsCulture plasticGrowth factorCellsGrowthRAMutants