Ligation of Integrin α3β1 by Laminin 5 at the Wound Edge Activates Rho-dependent Adhesion of Leading Keratinocytes on Collagen*
Nguyen B, Ren X, Schwartz M, Carter W. Ligation of Integrin α3β1 by Laminin 5 at the Wound Edge Activates Rho-dependent Adhesion of Leading Keratinocytes on Collagen*. Journal Of Biological Chemistry 2001, 276: 43860-43870. PMID: 11571278, DOI: 10.1074/jbc.m103404200.Peer-Reviewed Original ResearchConceptsHuman foreskin keratinocytesLaminin-5Wound edgeCultured human foreskin keratinocytesRho-independent mechanismEndogenous laminin-5Collagen adhesionSpreading of keratinocytesTransition of keratinocytesForeskin keratinocytesDermal collagenKeratinocytesIntegrin α3β1Wound cellsActivation signalsQuiescent keratinocytesCollagen