2018
Prevention of systemic autoimmunity by dietary modulation of the gut microbiota
Ruiz D, El-Beidaq A, Iniguez A, di Ricco M, Mubiro D, Vieira S, Ruff W, Sterpka J, Kriegel M. Prevention of systemic autoimmunity by dietary modulation of the gut microbiota. The Journal Of Immunology 2018, 200: 54.1-54.1. DOI: 10.4049/jimmunol.200.supp.54.1.Peer-Reviewed Original ResearchSystemic lupus erythematosusType I interferonShort-chain fatty acidsI interferonB6 miceTg miceAutoimmune diseasesGut microbiotaHuman systemic lupus erythematosusDendritic cell accumulationImmune-microbiota interactionsPrototypical autoimmune diseaseOnset of diseaseAmeliorate autoimmunityLupus inductionLupus manifestationsKidney involvementLupus pathogenesisLupus erythematosusTLR7 agonistSystemic autoimmunityPeyer's patchesDietary modulationCell accumulationGut microbial community
2014
Diet, microbiota and autoimmune diseases
Vieira S, Pagovich O, Kriegel M. Diet, microbiota and autoimmune diseases. Lupus 2014, 23: 518-526. PMID: 24763536, PMCID: PMC4009622, DOI: 10.1177/0961203313501401.Peer-Reviewed Original ResearchConceptsAutoimmune diseasesGut microbial communityGerm-free mouse modelDevelopment of autoimmunityDiet-derived metabolitesType 1 diabetesSeverity of diseaseLife-prolonging effectAdaptive immune systemAntiphospholipid syndromeAutoimmune modelSystemic lupusMultiple sclerosisGastrointestinal tractMurine modelMouse modelRodent modelsImmunomodulatory potentialCommensal bacteriaImmune systemCaloric restrictionGut microbiomeDietary changesLupusGut commensals