Studies of muscle proteins in embryonic myocardial cells of cardiac lethal mutant mexican axolotls (Ambystoma mexicanum) by use of heavy meromyosin binding and sodium dodecyl sulfate polyacrylamide gel electrophoresis.
Lemanski L, Mooseker M, Peachey L, Iyengar M. Studies of muscle proteins in embryonic myocardial cells of cardiac lethal mutant mexican axolotls (Ambystoma mexicanum) by use of heavy meromyosin binding and sodium dodecyl sulfate polyacrylamide gel electrophoresis. Journal Of Cell Biology 1976, 68: 375-388. PMID: 1107335, PMCID: PMC2109630, DOI: 10.1083/jcb.68.2.375.Peer-Reviewed Original ResearchConceptsMutant heartsRecessive mutant gene cMutant siblingsGene CHeart muscle differentiationMutant heart cellsHeavy meromyosin treatmentDalton bandMuscle proteinsGel electrophoresisSingle gene mutationsMutant embryonic heartsDifferent muscle proteinsEmbryonic myocardial cellsEarly developmental stagesSkeletal muscleSodium dodecyl sulfate gel electrophoresisDodecyl sulfate gel electrophoresisEmbryonic heart functionSodium dodecyl sulfate-polyacrylamide gel electrophoresisDodecyl sulfate-polyacrylamide gel electrophoresisSulfate-polyacrylamide gel electrophoresisHeavy meromyosin bindingMuscle differentiationMexican axolotl