2005
Myosin-1a Is Critical for Normal Brush Border Structure and Composition
Tyska M, Mackey A, Huang J, Copeland N, Jenkins N, Mooseker M. Myosin-1a Is Critical for Normal Brush Border Structure and Composition. Molecular Biology Of The Cell 2005, 16: 2443-2457. PMID: 15758024, PMCID: PMC1087248, DOI: 10.1091/mbc.e04-12-1116.Peer-Reviewed Original ResearchConceptsMyosin-1aWhole animal phenotypesWhole animal levelIntermediate filament proteinsEctopic recruitmentFunctional redundancyAnimal phenotypesBrush borderMyosin 1cOvert phenotypeBrush border structureFilament proteinsMembrane componentsCellular levelVertebrate myosinsPhenotypeSigns of stressAnimal levelKnockout miceSignificant perturbationsEnterocytesMultifunctional componentsGenesDistinct changesProtein
1998
Unconventional Myosins in Cell Movement, Membrane Traffic, and Signal Transduction
Mermall V, Post P, Mooseker M. Unconventional Myosins in Cell Movement, Membrane Traffic, and Signal Transduction. Science 1998, 279: 527-533. PMID: 9438839, DOI: 10.1126/science.279.5350.527.Peer-Reviewed Original ResearchConceptsSignal transductionCell movementMembrane trafficMembrane traffickingDisease-causing mutationsCellular functionsMyosin genesImportance of myosinUnconventional myosinMyosin functionCellular levelMolecular motorsMyosin structureTransductionMyosinGenesTraffickingActinMutationsBiochemicalFunctionMembersTargetIdentification