2003
Molecular Determinants of tGolgin-1 Function
Yoshino A, Marks M, Lemmon M. Molecular Determinants of tGolgin-1 Function. 2003 DOI: 10.21236/ada418143.Peer-Reviewed Original ResearchTrans-Golgi networkGRIP domainMammalian cellsC-terminal GRIP domainDynein/dynactin complexGRIP domain proteinsPeripheral membrane proteinsGTPase cascadeDomain proteinsDynactin complexGolgi networkMembrane proteinsCell motilityTurn bindsGolgi complexProtein resultsMolecular determinantsProteinTumor developmentOrthologuesCellsDomainRNAiEndosomesYeastGenome-wide analysis of signaling domain function
Yu JW, Lemmon MA. Genome-wide analysis of signaling domain function. Current Opinion In Chemical Biology 2003, 7: 103-109. PMID: 12547434, DOI: 10.1016/s1367-5931(02)00008-x.Peer-Reviewed Original Research
1998
Identification and analysis of PH domain‐containing targets of phosphatidylinositol 3‐kinase using a novel in vivo assay in yeast
Isakoff S, Cardozo T, Andreev J, Li Z, Ferguson K, Abagyan R, Lemmon M, Aronheim A, Skolnik E. Identification and analysis of PH domain‐containing targets of phosphatidylinositol 3‐kinase using a novel in vivo assay in yeast. The EMBO Journal 1998, 17: 5374-5387. PMID: 9736615, PMCID: PMC1170863, DOI: 10.1093/emboj/17.18.5374.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceBlood ProteinsCell MembraneConsensus SequenceConserved SequenceFungal ProteinsModels, MolecularMutationPhosphatidylinositol 3-KinasesPhosphatidylinositol PhosphatesPhosphoproteinsProtein BindingRas ProteinsRecombinant Fusion ProteinsSaccharomyces cerevisiaeSecond Messenger SystemsSequence Homology, Amino AcidConceptsPI3K productsPH domainNon-permissive temperaturePH domain-containing proteinsRas exchange factorK productDomain-containing proteinsPleckstrin homology domainExchange factorHomology domainYeast SaccharomycesNovel cDNAConsensus sequenceFusion proteinSecond messengerCellular responsesPI3KAmino acidsHigh affinityYeastYeast growthProteinPhosphatidylinositolNovel assayPowerful approach