Identification and localization of TRPC channels in the rat kidney
Goel M, Sinkins W, Zuo C, Estacion M, Schilling W. Identification and localization of TRPC channels in the rat kidney. American Journal Of Physiology. Renal Physiology 2005, 290: f1241-f1252. PMID: 16303855, DOI: 10.1152/ajprenal.00376.2005.Peer-Reviewed Original ResearchConceptsTubular cellsDuct cellsTransient receptor potential channelsG protein-coupled membrane receptorsPresence of TRPC1Aquaporin-2Western blot analysisMesangial cell culturesKidney sectionsProximal tubulesOuter medullaRat kidneyTRPC channelsRenal nephronKidney lysateTRPC3Immunopositive labelingTRPC1PLC-dependent signalingRat kidney lysateInner medullaAffinity-purified antibodiesPrinciple cellsPolarized culturesCell lines