2013
Immunoregulatory Neuropeptides
Ganea D, Skarica M. Immunoregulatory Neuropeptides. 2013, 144-160. DOI: 10.1002/9781118314814.ch7.Peer-Reviewed Original ResearchVasoactive intestinal peptideCentral nervous systemAnti-inflammatory neuropeptidesImmunoregulatory neuropeptideParasympathetic innervationAutoimmune diseasesImmunomodulatory roleIntestinal peptideImmune cellsLymphoid organsAdaptive immunityVivo effectsNervous systemImmune systemImmune sourcesClinical useNeuropeptidesMajor signaling pathwaysSignaling pathwaysPeptide familyReceptorsPleiotropic effectsInnervationChemokinesCytokines
2011
Novel mechanisms of immune modulation of natalizumab in multiple sclerosis patients
Skarica M, Eckstein C, Whartenby K, Calabresi P. Novel mechanisms of immune modulation of natalizumab in multiple sclerosis patients. Journal Of Neuroimmunology 2011, 235: 70-76. PMID: 21550672, DOI: 10.1016/j.jneuroim.2011.02.010.Peer-Reviewed Original ResearchConceptsNatalizumab therapyPeripheral bloodMonth timepointProportion of CD20Proportion of CD4Number of CD14Multiple sclerosis patientsImmune cell compositionHematopoetic stem cellsPercentage of cellsMechanism of actionNatalizumab treatmentRRMS patientsMS patientsNK cellsSclerosis patientsTreatment onsetCytokine productionImmune compositionImmune modulationImmune cellsT cellsB cellsPatientsTherapy
2010
Anti-inflammatory property of the cannabinoid receptor-2-selective agonist in spinal cord injury (35.11)
Adhikary S, Hongbo L, Skarica M, Tuma R, Ganea D. Anti-inflammatory property of the cannabinoid receptor-2-selective agonist in spinal cord injury (35.11). The Journal Of Immunology 2010, 184: 35.11-35.11. DOI: 10.4049/jimmunol.184.supp.35.11.Peer-Reviewed Original ResearchAcute spinal cord injurySpinal cord injuryAgonist treatmentImmune cellsCannabinoid receptor-2 selective agonistCord injurySpinal cordAnimal models of CNS disordersContusion model of spinal cord injuryInfiltration of immune cellsModels of CNS disordersT-cell-activating cytokinesTreat neuropathic painExpression of inflammatory moleculesModel of spinal cord injuryModel of acute spinal cord injuryInflammatory immune cellsToll-like receptorsO-1966Neuropathic painCannabinoid receptorsBladder functionRecovery of motorIL-23Anti-inflammatory properties