2024
Scoring PD-L1 Expression in Urothelial Carcinoma: An International Multi-Institutional Study on Comparison of Manual and Artificial Intelligence Measurement Model (AIM-PD-L1) Pathology Assessments
Rüschoff J, Kumar G, Badve S, Jasani B, Krause E, Rioux-Leclercq N, Rojo F, Martini M, Cheng L, Tretiakova M, Mitchell C, Anders R, Robert M, Fahy D, Pyle M, Le Q, Yu L, Glass B, Baxi V, Babadjanova Z, Pratt J, Brutus S, Karasarides M, Hartmann A. Scoring PD-L1 Expression in Urothelial Carcinoma: An International Multi-Institutional Study on Comparison of Manual and Artificial Intelligence Measurement Model (AIM-PD-L1) Pathology Assessments. Virchows Archiv 2024, 484: 597-608. PMID: 38570364, DOI: 10.1007/s00428-024-03795-8.Peer-Reviewed Original ResearchConceptsPD-L1 expressionImmune checkpoint inhibitorsPD-L1Tumor cellsAssess programmed death ligand 1Assessment of PD-L1 expressionScoring of PD-L1 expressionInternational multi-institutional studyPD-L1 expression analysisFood and Drug Administration-approvedPD-L1 stainingDeath-ligand 1Drug Administration-approvedMulti-institutional studyCheckpoint inhibitorsUrothelial carcinomaPathological assessmentBiomarker expressionInterobserver variabilityLigand 1Cancer treatmentExpert pathologistsClinical settingMultinational studyPositive rate
2000
Evidence for the Neoplastic Transformation of Von-Meyenburg Complexes
Jain D, Sarode V, Abdul–Karim F, Homer R, Robert M. Evidence for the Neoplastic Transformation of Von-Meyenburg Complexes. The American Journal Of Surgical Pathology 2000, 24: 1131-1139. PMID: 10935654, DOI: 10.1097/00000478-200008000-00011.Peer-Reviewed Original ResearchConceptsVon Meyenburg complexesAdenomatous lesionsNeoplastic transformationTumor-like nodulesCongenital hepatic fibrosisDuctal plate malformationPattern of fibrosisBackground of fibrosisCases of cholangiocarcinomaEpithelial membrane antigenYears of ageSmall renal cystsPortal hypertensionDuctular proliferationMicronodular cirrhosisHepatic fibrosisTomographic scanHistologic examinationImmunohistochemical stainingRenal cystsCentral veinMembrane antigenCarcinoembryonic antigenCirrhosisCholangiocarcinoma
1996
Diffuse colonic mantle cell lymphoma in a patient with presumed ulcerative colitis: detection of a precursor monoclonal lymphoid population using polymerase chain reaction and immunohistochemistry.
Robert M, Kuo F, Longtine J, Sklar J, Schrock T, Weidner N. Diffuse colonic mantle cell lymphoma in a patient with presumed ulcerative colitis: detection of a precursor monoclonal lymphoid population using polymerase chain reaction and immunohistochemistry. The American Journal Of Surgical Pathology 1996, 20: 1024-31. PMID: 8712289, DOI: 10.1097/00000478-199608000-00011.Peer-Reviewed Original ResearchConceptsUlcerative colitisColonic lymphomaMantle cell lymphomaMucosal changesCell lymphomaInflammatory mucosal changesPrimary colonic lymphomaSevere ulcerative colitisImmunoglobulin heavy chain gene rearrangementHigh-grade morphologyHeavy chain gene rearrangementMonoclonal lymphoid populationLate complicationsMucosal injuryUnderlying diseasePrimary lymphomaFurther workupInitial diagnosisResection specimenPolymerase chain reactionSuperficial biopsiesLymphoid proliferationsColitisLymphoid populationsLymphoma