2018
Peptidoglycan editing by a specific ld-transpeptidase controls the muramidase-dependent secretion of typhoid toxin
Geiger T, Pazos M, Lara-Tejero M, Vollmer W, Galán JE. Peptidoglycan editing by a specific ld-transpeptidase controls the muramidase-dependent secretion of typhoid toxin. Nature Microbiology 2018, 3: 1243-1254. PMID: 30250245, PMCID: PMC7464686, DOI: 10.1038/s41564-018-0248-x.Peer-Reviewed Original ResearchConceptsProtein export mechanismProtein secretion mechanismsTyphoid toxinEssential virulence factorBacterial poleMammalian cellsPeptidoglycan layerMost bacterial pathogensOuter membraneExport mechanismSecretion mechanismToxin secretionBacterial speciesTranslocation processTrans sideVirulence factorsBacterial pathogensExtracellular spaceTransport pathwaysTarget cellsToxinTyphoid feverCellsSubsequent releaseSecretion
2014
Novel Components of the Flagellar System in Epsilonproteobacteria
Gao B, Lara-Tejero M, Lefebre M, Goodman AL, Galán JE. Novel Components of the Flagellar System in Epsilonproteobacteria. MBio 2014, 5: 10.1128/mbio.01349-14. PMID: 24961693, PMCID: PMC4073491, DOI: 10.1128/mbio.01349-14.Peer-Reviewed Original ResearchConceptsBacterial pathogen Campylobacter jejuniPathogen Campylobacter jejuniFlagellar systemBacterial speciesNovel componentGenetic screenFlagellar structureMost bacteriaMolecular basisHigh-throughput genetic screensFlagellar apparatusComprehensive genetic screenDiverse bacterial speciesCampylobacter jejuniDifferent bacterial speciesGroup of bacteriaBacterial poleBacterial organellesFlagellar machineryTransposon mutagenesisNext-generation sequencingEpsilonproteobacteriaFlagellaRecent studiesSpecies