2017
Metabolic and fitness determinants for in vitro growth and intestinal colonization of the bacterial pathogen Campylobacter jejuni
Gao B, Vorwerk H, Huber C, Lara-Tejero M, Mohr J, Goodman AL, Eisenreich W, Galán JE, Hofreuter D. Metabolic and fitness determinants for in vitro growth and intestinal colonization of the bacterial pathogen Campylobacter jejuni. PLOS Biology 2017, 15: e2001390. PMID: 28542173, PMCID: PMC5438104, DOI: 10.1371/journal.pbio.2001390.Peer-Reviewed Original ResearchMeSH KeywordsAbsorption, PhysiologicalAmino AcidsAnimalsAnti-Bacterial AgentsBacterial ProteinsCampylobacter InfectionsCampylobacter jejuniCation Transport ProteinsDNA Transposable ElementsDysbiosisGastroenteritisGene DeletionGenetic Association StudiesGenome, BacterialGenomic LibraryMice, Inbred C57BLMicrobial ViabilityModels, BiologicalMutagenesis, InsertionalMutationConceptsCampylobacter jejuniFood-producing animalsInfectious causesFood-borne illnessMost infectionsMouse modelHuman infectionsIntestinal colonizationIntestinal tractInfectionJejuni colonizationMouse intestineNext-generation sequencingIntracellular ion homeostasisC. jejuniFitness determinantsCertain nutrientsPathogenic strainsJejuniMetabolic requirementsComprehensive genome-wide analysisBacterial pathogen Campylobacter jejuniPathogen Campylobacter jejuniAnimalsGenome-wide analysis
2014
Novel Components of the Flagellar System in Epsilonproteobacteria
Gao B, Lara-Tejero M, Lefebre M, Goodman AL, Galán JE. Novel Components of the Flagellar System in Epsilonproteobacteria. MBio 2014, 5: 10.1128/mbio.01349-14. PMID: 24961693, PMCID: PMC4073491, DOI: 10.1128/mbio.01349-14.Peer-Reviewed Original ResearchConceptsBacterial pathogen Campylobacter jejuniPathogen Campylobacter jejuniFlagellar systemBacterial speciesNovel componentGenetic screenFlagellar structureMost bacteriaMolecular basisHigh-throughput genetic screensFlagellar apparatusComprehensive genetic screenDiverse bacterial speciesCampylobacter jejuniDifferent bacterial speciesGroup of bacteriaBacterial poleBacterial organellesFlagellar machineryTransposon mutagenesisNext-generation sequencingEpsilonproteobacteriaFlagellaRecent studiesSpecies