2024
TimelinePTC: Development of a unified interface for pathways to care collection, visualization, and collaboration in first episode psychosis
Mathis W, Ferrara M, Cahill J, Karmani S, Tayfur S, Srihari V. TimelinePTC: Development of a unified interface for pathways to care collection, visualization, and collaboration in first episode psychosis. PLOS ONE 2024, 19: e0302116. PMID: 39028697, PMCID: PMC11259254, DOI: 10.1371/journal.pone.0302116.Peer-Reviewed Original ResearchConceptsPathways to CareDuration of untreated psychosisManual transcription errorsDevelopment of targeted interventionsReduce duration of untreated psychosisHealthcare accessibility researchReal-time data entryImprove patient outcomesEpisode psychosisCare pathwaysPatient journeyHealthcare contextPatient outcomesPaper-basedConversion of collected dataFEP treatmentData collection processNew HavenData collection methodsData entryTranscription errorsUntreated psychosisOpen-source codebaseData collectionWeb-based toolFirst episode psychoses in people over-35 years old: uncovering potential actionable targets for early intervention services
Ferrara M, Domenicano I, Marchi A, Zaffarami G, Onofrio A, Benini L, Sorio C, Gentili E, Murri M, Toffanin T, Little J, Grassi L. First episode psychoses in people over-35 years old: uncovering potential actionable targets for early intervention services. Psychiatry Research 2024, 339: 116034. PMID: 38906051, DOI: 10.1016/j.psychres.2024.116034.Peer-Reviewed Original ResearchLong-acting injectable antipsychoticsFirst-episode psychosisEarly intervention servicesPrescribing long-acting injectable antipsychoticsNon-affective first-episode psychosisIntervention servicesCommunity psychiatric servicesInjectable antipsychoticsPsychotic onsetEpisode psychosisAffective psychosisPsychiatric servicesPsychosisExclusion of patientsAccess treatmentClinical characteristicsRetrospective studyOlder patientsPatientsAntipsychoticsAntidepressantsAge groupsWomenGroupIndividualsThe Italian adaptation of the Mini‐SIPS, a tool for early detection of individuals at clinical high risk and first episode of psychosis: A preliminary study of implementation in an Italian FEP program
Ferrara M, Basaldella M, Vacca F, Woods S, Walsh B, Cannon T, Srihari V, Grassi L. The Italian adaptation of the Mini‐SIPS, a tool for early detection of individuals at clinical high risk and first episode of psychosis: A preliminary study of implementation in an Italian FEP program. Early Intervention In Psychiatry 2024 PMID: 38769052, DOI: 10.1111/eip.13548.Peer-Reviewed Original ResearchClinical high riskFirst-episode psychosisDSM-5-Attenuated Psychosis SyndromeItalian adaptationPsychosis syndromeDSM-5FEP programsEarly stages of psychosisItalian versionFirst-episode psychosis servicesFull-blown psychosisStages of psychosisEpisode of psychosisClinical structured interviewEpisode psychosisEstablished psychosisTrained psychologistsPsychiatric historyPsychosisPsychosis servicesHigh riskStructured interviewsClinical settingEarly detection of individualsAssess validityAntipsychotic drugs in first-episode psychosis: a target trial emulation in the FEP-CAUSAL Collaboration
Szmulewicz A, Martínez-Alés G, Logan R, Ferrara M, Kelly C, Fredrikson D, Gago J, Conderino S, Díaz-Caneja C, Galvañ J, Thorpe L, Srihari V, Yatham L, Sarpal D, Shinn A, Arango C, Öngür D, Hernán M, Collaboration O. Antipsychotic drugs in first-episode psychosis: a target trial emulation in the FEP-CAUSAL Collaboration. American Journal Of Epidemiology 2024, 193: 1081-1087. PMID: 38576166, DOI: 10.1093/aje/kwae029.Peer-Reviewed Original ResearchFirst-episode psychosisFirst-generation agentsAntipsychotic therapyAntipsychotic drugsPsychosis onsetPsychotic disordersEpisode psychosisAripiprazolePaliperidoneRisk of hospitalizationPsychosisTarget trialsRisperidoneOlanzapineFirst-line therapyTreatment discontinuationEUFESTObservational cohortAntipsychoticsQuetiapineRandomized trialsPrimary outcomeAbsolute riskRisk differenceClinical questions
2023
579. Benchmarking Observational Analyses Against Randomized Trial Results: An Application to First Episode Psychosis
Szmulewicz A, Martinez-Ales G, Ferrara M, Fredrikson D, Gago J, Srihari V, Yatham L, Conderino S, Shinn A, Ongur D, Hernán M. 579. Benchmarking Observational Analyses Against Randomized Trial Results: An Application to First Episode Psychosis. Biological Psychiatry 2023, 93: s328-s329. DOI: 10.1016/j.biopsych.2023.02.819.Peer-Reviewed Original Research
2019
Early intervention service for first episode psychosis in Modena, Northern Italy: The first hundred cases
Ferrara M, Tedeschini E, Baccari F, Musella V, Vacca F, Mazzi F, Ferri M, Srihari V, Starace F, Group F. Early intervention service for first episode psychosis in Modena, Northern Italy: The first hundred cases. Early Intervention In Psychiatry 2019, 13: 1011-1017. PMID: 30672134, DOI: 10.1111/eip.12788.Peer-Reviewed Original ResearchConceptsEarly intervention servicesClinical improvementMedian ageIntervention servicesCommunity mental health centerCommunity outpatient servicesPsychiatric hospital unitMeaningful clinical improvementFirst-episode psychosisModel of careNon-affective psychosisNation Outcome ScalesMental health centersHigher median ageEarly detection effortsRefinement of treatmentMain referralsPharmacological consultationYounger patientsUntreated psychosisOutcome ScaleGeneral practitionersEpisode psychosisHealth centersOutpatient services