Effect of Expanded Newborn Screening for Biochemical Genetic Disorders on Child Outcomes and Parental Stress
Waisbren SE, Albers S, Amato S, Ampola M, Brewster TG, Demmer L, Eaton RB, Greenstein R, Korson M, Larson C, Marsden D, Msall M, Naylor EW, Pueschel S, Seashore M, Shih VE, Levy HL. Effect of Expanded Newborn Screening for Biochemical Genetic Disorders on Child Outcomes and Parental Stress. JAMA 2003, 290: 2564-2572. PMID: 14625333, DOI: 10.1001/jama.290.19.2564.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttitude to HealthChildChild DevelopmentChild, PreschoolDevelopmental DisabilitiesFalse Positive ReactionsFemaleHealth StatusHospitalizationHumansInfantInfant, NewbornIntellectual DisabilityMaleMass SpectrometryMetabolism, Inborn ErrorsNeonatal ScreeningParentsProspective StudiesStress, PsychologicalConceptsFalse-positive screening resultsBiochemical genetic disordersParental Stress IndexNormal resultsNewborn screeningMothers of childrenFalse-positive resultsScreening resultsGenetic disordersNormal screening resultsMonths of lifeFalse-positive groupImproved health outcomesExpanded Newborn ScreeningStress indexInception cohortScreened groupProspective studyChild healthClinical identificationHealth outcomesLimited screeningParent-child dysfunctionDisordersMental retardation