2024
Efficacy and Neural Mechanisms of Mindfulness Meditation Among Adults With Internet Gaming Disorder
Ni H, Wang H, Ma X, Li S, Liu C, Song X, Potenza M, Dong G. Efficacy and Neural Mechanisms of Mindfulness Meditation Among Adults With Internet Gaming Disorder. JAMA Network Open 2024, 7: e2416684. PMID: 38888924, PMCID: PMC11185988, DOI: 10.1001/jamanetworkopen.2024.16684.Peer-Reviewed Original ResearchConceptsInternet gaming disorderDSM-5-TRProgressive muscle relaxationMindfulness meditationProgressive muscle relaxation groupNeural mechanismsGaming cravingsAddiction severityDecreased cravingFunctional connectivityAssociated with decreased brain activitySeverity of internet gaming disorderInternet gaming disorder severityTreating Internet Gaming DisorderBlood oxygen level-dependent signalCue-craving taskMedial frontal gyrusPotential neural mechanismsProgressive muscle relaxation trainingBilateral lentiform nucleusFrontal gyrusIncreased mindfulnessBrain measuresGaming disorderBrain regions
2023
Neural mechanisms linked to treatment outcomes and recovery in substance-related and addictive disorders
Mestre-Bach G, Potenza M. Neural mechanisms linked to treatment outcomes and recovery in substance-related and addictive disorders. Dialogues In Clinical Neuroscience 2023, 25: 75-91. PMID: 37594217, PMCID: PMC10444012, DOI: 10.1080/19585969.2023.2242359.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsBehavior, AddictiveBrainHumansInternet Addiction DisorderMental DisordersTreatment OutcomeConceptsNeural mechanismsAddictive disordersPotential neural mechanismsTreatment development effortsInternet gaming disorderBrain processesSubstance use disordersAdvanced analytic approachesGaming disorderImpulse controlTreatment developmentUse disordersPsychiatric conditionsExtant dataTreatment utilityAddictionDisordersAnalytic approachTreatment outcomesNarrative reviewIntervention administrationMedication challengePresent reviewMain modelsContextDistinct neural networks predict cocaine versus cannabis treatment outcomes
Lichenstein S, Kohler R, Ye F, Potenza M, Kiluk B, Yip S. Distinct neural networks predict cocaine versus cannabis treatment outcomes. Molecular Psychiatry 2023, 28: 3365-3372. PMID: 37308679, PMCID: PMC10713861, DOI: 10.1038/s41380-023-02120-0.Peer-Reviewed Original ResearchConceptsConnectome-based predictive modelingCognitive behavior therapyCognitive behavioral therapySubstance use disordersCannabis abstinenceNeural mechanismsBehavior therapyDistinct neural networksComputer-based trainingCannabis use disorderFMRI scanningNeural predictorsStudy 1Study 2Treatment outcomesContingency managementPrior workComparison subjectsNetwork strengthUse disordersNovel treatment targetsAbstinenceIndependent samplesCocaine abstinenceTreatment respondersFeatures Linked to Treatment Outcomes in Behavioral Addictions and Related Disorders
Mestre-Bach G, Potenza M. Features Linked to Treatment Outcomes in Behavioral Addictions and Related Disorders. International Journal Of Environmental Research And Public Health 2023, 20: 2873. PMID: 36833569, PMCID: PMC9957199, DOI: 10.3390/ijerph20042873.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2018
fMRI Stroop and behavioral treatment for cocaine-dependence: Preliminary findings in methadone-maintained individuals
DeVito EE, Kober H, Carroll KM, Potenza MN. fMRI Stroop and behavioral treatment for cocaine-dependence: Preliminary findings in methadone-maintained individuals. Addictive Behaviors 2018, 89: 10-14. PMID: 30240978, PMCID: PMC6374034, DOI: 10.1016/j.addbeh.2018.09.005.Peer-Reviewed Original ResearchConceptsCocaine use disorderStroop effectBehavioral treatmentComputer-based cognitive behavioral therapyColor-word Stroop taskCognitive neuroscience methodsCognitive behavioral therapyCocaine-dependent individualsCocaine abstinenceCognitive controlStroop taskNeuroscience methodsMethadone-maintained individualsTreatment abstinenceLingual gyrusStroopCingulate gyrusUse disordersCocaine usersTreatment mechanismsAbstinenceBetter treatment outcomesPreliminary findingsGyrusParticipants
1999
Olanzapine Treatment of Children, Adolescents, and Adults with Pervasive Developmental Disorders
Potenza M, Holmes J, Kanes S, McDougle C. Olanzapine Treatment of Children, Adolescents, and Adults with Pervasive Developmental Disorders. Journal Of Clinical Psychopharmacology 1999, 19: 37-44.. PMID: 9934941, DOI: 10.1097/00004714-199902000-00008.Peer-Reviewed Original ResearchConceptsPervasive developmental disorderClinical Global Impression ScaleWeight gainTolerability of olanzapineLiver function abnormalitiesExtrapyramidal side effectsGlobal Impression ScaleGlobal improvement itemTreatment of childrenSignificant adverse effectsDevelopmental disordersSelf-injurious behaviorClinical respondersOlanzapine treatmentFunction abnormalitiesDaily doseOverall symptomsPatient populationImpression ScalePrincipal diagnosisMotor restlessnessProspective fashionWeek 4Related symptomsSide effects