Tolerability Profile of Atypical Antipsychotics in Children and Adolescents
Stigler K, Potenza M, McDougle C. Tolerability Profile of Atypical Antipsychotics in Children and Adolescents. Pediatric Drugs 2001, 3: 927-942. PMID: 11772153, DOI: 10.2165/00128072-200103120-00005.Peer-Reviewed Original ResearchConceptsUse of clozapineExtrapyramidal symptomsAtypical antipsychoticsBodyweight gainTolerability profileGlucose intoleranceBlood glucoseReceptor profileRisk of EPSAdverse effectsCommon adverse effectsLiver function studiesTreatment-refractory diseasePotential treatment optionReceptor interaction profilesOnset of maniaLack of evidenceQTc prolongationBaseline electrocardiogramTreatment optionsSeizure riskCardiovascular illnessClose monitoringClozapineAntipsychotics