2020
Disrupted prefrontal regulation of striatum-related craving in Internet gaming disorder revealed by dynamic causal modeling: results from a cue-reactivity task
Dong GH, Wang M, Zheng H, Wang Z, Du X, Potenza MN. Disrupted prefrontal regulation of striatum-related craving in Internet gaming disorder revealed by dynamic causal modeling: results from a cue-reactivity task. Psychological Medicine 2020, 51: 1549-1561. PMID: 32102722, DOI: 10.1017/s003329172000032x.Peer-Reviewed Original ResearchConceptsInternet gaming disorderPosterior cingulate cortexRecreational game useIGD subjectsRGU subjectsNeurobiological markersGaming disorderCue-craving taskCue-reactivity taskGaming-related cuesCue-related cravingDynamic causal modelingPossible neurobiological mechanismsCognitive controlGaming cuesNeutral cuesUseful neurobiological markerPrefrontal regulationBrain responsesNeurobiological mechanismsLeft hemisphereCausal modelingCingulate cortexDirectional connectivityGame use
2019
Neurofunctional Differences Related to Methamphetamine and Sexual Cues in Men With Shorter and Longer Term Abstinence Methamphetamine Dependence
Chen S, Huang S, Yang C, Cai W, Chen H, Hao W, Liu T, Wang X, Worhunsky P, Potenza M. Neurofunctional Differences Related to Methamphetamine and Sexual Cues in Men With Shorter and Longer Term Abstinence Methamphetamine Dependence. The International Journal Of Neuropsychopharmacology 2019, 23: 135-145. PMID: 31995187, PMCID: PMC7171928, DOI: 10.1093/ijnp/pyz069.Peer-Reviewed Original ResearchConceptsHealthy comparison menFrontal cortex activationLong-term methamphetamine abstinenceSexual cuesNeutral cuesMethamphetamine cuesNeurofunctional differencesComparison menCortex activationLeft superior frontal cortexCue-related activationsNeutral visual cuesAnterior insula activationCue-reactivity taskAnterior insula responseVentromedial prefrontal cortexHealthy comparison participantsMethamphetamine abstinenceMethamphetamine dependenceFunctional magnetic resonanceWhole-brain analysisAbstinence groupSuperior frontal cortexInsula activationInsula response