2023
Distinct neural networks predict cocaine versus cannabis treatment outcomes
Lichenstein S, Kohler R, Ye F, Potenza M, Kiluk B, Yip S. Distinct neural networks predict cocaine versus cannabis treatment outcomes. Molecular Psychiatry 2023, 28: 3365-3372. PMID: 37308679, PMCID: PMC10713861, DOI: 10.1038/s41380-023-02120-0.Peer-Reviewed Original ResearchConceptsConnectome-based predictive modelingCognitive behavior therapyCognitive behavioral therapySubstance use disordersCannabis abstinenceNeural mechanismsBehavior therapyDistinct neural networksComputer-based trainingCannabis use disorderFMRI scanningNeural predictorsStudy 1Study 2Treatment outcomesContingency managementPrior workComparison subjectsNetwork strengthUse disordersNovel treatment targetsAbstinenceIndependent samplesCocaine abstinenceTreatment responders
2022
Neural activations to loss anticipation mediates the association between difficulties in emotion regulation and screen media activities among early adolescent youth: A moderating role for depression
Zhang J, Zhou N, Song K, Zou B, Xu L, Fu Y, Geng X, Wang Z, Li X, Potenza M, Nan Y, Zhang J. Neural activations to loss anticipation mediates the association between difficulties in emotion regulation and screen media activities among early adolescent youth: A moderating role for depression. Developmental Cognitive Neuroscience 2022, 58: 101186. PMID: 36516611, PMCID: PMC9764194, DOI: 10.1016/j.dcn.2022.101186.Peer-Reviewed Original ResearchConceptsReward/loss processingDorsolateral prefrontal cortexProcessing of emotionsScreen media activitiesAnterior insulaLoss processingEmotion regulationBrain activationRight dorsolateral prefrontal cortexMonetary incentive delay taskDepressive symptomsNegative emotional situationsEarly adolescent youthIncentive delay taskNegative emotional statesLeft anterior insulaPotential mediating factorsAI activationNeural correlatesFMRI scanningDelay taskEmotional situationsEmotional statesLoss anticipationMediation model