Functional expression and characterization of human D2 and D3 dopamine receptors
Potenza M, Graminski G, Schmauss C, Lerner. Functional expression and characterization of human D2 and D3 dopamine receptors. Journal Of Neuroscience 1994, 14: 1463-1476. PMID: 7907363, PMCID: PMC6577580, DOI: 10.1523/jneurosci.14-03-01463.1994.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiological AssayCyclic AMPDopamine AgentsDopamine AntagonistsHumansLigandsMelanocyte-Stimulating HormonesMelanophoresMelatoninPertussis ToxinPigments, BiologicalReceptors, DopamineReceptors, Dopamine D2Receptors, Dopamine D3TetrahydronaphthalenesVirulence Factors, BordetellaXenopus laevisConceptsD3 receptorsCAMP accumulationGi protein-coupled receptorHuman D2Selective dopaminergic agonistsDose-dependent mannerIC50 value determinationDopaminergic agonistsMelanocyte receptorsPertussis toxinD3 dopamineAgonistsReceptorsPigment granule aggregationAntagonistD2RXenopus laevis melanophoresSimilar concentrationsFunctional expressionPigment aggregationD3R.Initial feasibility studyFunctional characteristicsCultured Xenopus laevis melanophoresNew bioassay