Anandamide and 2-arachidonoylglycerol baseline plasma concentrations and their clinical correlate in gambling disorder
Baenas I, Solé-Morata N, Granero R, Fernández-Aranda F, Pujadas M, Mora-Maltas B, Lucas I, Gómez-Peña M, Moragas L, del Pino-Gutiérrez A, Tapia J, de la Torre R, Potenza M, Jiménez-Murcia S. Anandamide and 2-arachidonoylglycerol baseline plasma concentrations and their clinical correlate in gambling disorder. European Psychiatry 2023, 66: e97. PMID: 37937379, PMCID: PMC10755577, DOI: 10.1192/j.eurpsy.2023.2460.Peer-Reviewed Original ResearchConceptsHealthy control subjectsPlasma concentrationsBaseline plasma concentrationsPeripheral blood samplesBrain reward pathwaysGambling disorderSemi-structured clinical interviewConcentrations of endocannabinoidsNeuropsychological variablesAddiction-related disordersGD severityClinical correlatesControl subjectsAdult outpatientsEndocannabinoid systemBlood samplesClinical InterviewPlasma AEA concentrationsEndogenous ligandReward pathwayClinical groupsEndocannabinoidsAEA concentrationsPsychometric assessmentNeurobiological substrates