2023
Changes in synaptic markers after administration of ketamine or psychedelics: a systematic scoping review
Zhornitsky S, Oliva H, Jayne L, Allsop A, Kaye A, Potenza M, Angarita G. Changes in synaptic markers after administration of ketamine or psychedelics: a systematic scoping review. Frontiers In Psychiatry 2023, 14: 1197890. PMID: 37435405, PMCID: PMC10331617, DOI: 10.3389/fpsyt.2023.1197890.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAdministration of ketamineSynaptic markersSubstance use disordersPrefrontal cortexSingle doseBasal conditionsStress-related reductionPsilocybin/psilocinVerbal memory performanceWeb of ScienceKetamine treatmentSystematic scoping reviewLysergic acid diethylamideSynaptic densityClinical studiesSynaptophysin 1PRISMA guidelinesSynapsin 1Use disordersPlace preferenceAbuse liabilitySynaptic changesKetaminePSD-95Study designUse of experimental medicine approaches for the development of novel psychiatric treatments based on orexin receptor modulation
Beckenstrom A, Coloma P, Dawson G, Finlayson A, Malik A, Post A, Steiner M, Potenza M. Use of experimental medicine approaches for the development of novel psychiatric treatments based on orexin receptor modulation. Neuroscience & Biobehavioral Reviews 2023, 147: 105107. PMID: 36828161, PMCID: PMC10165155, DOI: 10.1016/j.neubiorev.2023.105107.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsExperimental medicine approachPerformance outcome measuresPsychiatric disordersMedicine approachReal-world clinical practiceOrexin neuropeptide systemMarkers of efficacyPatient advocacy groupsOrexin modulationReceptor modulationSymptom evaluationReceptor modulatorsClinical studiesMood disordersPreclinical studiesNeuropeptide systemsPsychiatric treatmentAnimal modelsPathological mechanismsClinical practiceClinical researchClinical useBrain functionTranslational researchPotential target
2022
Mechanistic Effects and Use of N-acetylcysteine in Substance Use Disorders
Greenberg N, Farhadi F, Kazer B, Potenza M, Angarita G. Mechanistic Effects and Use of N-acetylcysteine in Substance Use Disorders. Current Behavioral Neuroscience Reports 2022, 9: 124-143. DOI: 10.1007/s40473-022-00250-3.Peer-Reviewed Original ResearchSubstance use disordersN-acetylcysteineUse disordersEfficacy of NACTreatment of SUDsGlial glutamate transporter-1Glutamate transporter 1Drug-seeking behaviorCue-induced reinstatementNAC useAdjunctive useClinical studiesGlutamate homeostasisGlutamate signalingNeurobiological effectsClinical approachRelapse behaviorSubcortical regionsSynaptic plasticityFunctional connectivity networksPrefrontal cortexBehavioral interventionsTransporter 1Oxidative stressImpulsive behavior
2020
Smartphone Applications for Mindfulness Training in the Treatment of Substance Use Disorders
Garrison K, O'Malley S, Brewer J, Potenza M. Smartphone Applications for Mindfulness Training in the Treatment of Substance Use Disorders. 2020, 428-438. DOI: 10.1093/oxfordhb/9780190218058.013.36.ChaptersSubstance use disordersUse disordersClinical testingEvidence-based clinical practice guidelinesMental healthMindfulness appClinical practice guidelinesMindfulness trainingInitial clinical testingSubstance use treatmentClinical outcomesClinical benefitSmartphone appClinical studiesPractice guidelinesUse treatmentDisordersTreatmentMeditation appTrialsHealthAreas of focus