2023
Use of experimental medicine approaches for the development of novel psychiatric treatments based on orexin receptor modulation
Beckenstrom A, Coloma P, Dawson G, Finlayson A, Malik A, Post A, Steiner M, Potenza M. Use of experimental medicine approaches for the development of novel psychiatric treatments based on orexin receptor modulation. Neuroscience & Biobehavioral Reviews 2023, 147: 105107. PMID: 36828161, PMCID: PMC10165155, DOI: 10.1016/j.neubiorev.2023.105107.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsExperimental medicine approachPerformance outcome measuresPsychiatric disordersMedicine approachReal-world clinical practiceOrexin neuropeptide systemMarkers of efficacyPatient advocacy groupsOrexin modulationReceptor modulationSymptom evaluationReceptor modulatorsClinical studiesMood disordersPreclinical studiesNeuropeptide systemsPsychiatric treatmentAnimal modelsPathological mechanismsClinical practiceClinical researchClinical useBrain functionTranslational researchPotential target
2021
Neurobiology of Addiction
Gogliettino A, Potenza M, Yip S, Zakiniaeiz Y, Zhai Z. Neurobiology of Addiction. DeckerMed Medical Cannabis 2021 DOI: 10.2310/cannabis.13044.ChaptersFunctional magnetic resonance imagingBrain functionCo-occurring disordersCognitive aspectsGambling disorderBehavioral addictionsCognitive functionAddictive disordersSubstance addictionDSM-5Substance useNegative consequencesNeurochemical systemsNegative healthVisual representationAddictionSocial consequencesExtant literatureNeurobiologyDisordersCurrent treatment strategiesQuality of lifeMagnetic resonance imagingPositron emission tomographyGamblingNeurobiology of Addiction
Gogliettino A, Potenza M, Yip S, Zakiniaeiz Y, Zhai Z. Neurobiology of Addiction. DeckerMed Psychiatry 2021 DOI: 10.2310/psych.13044.ChaptersFunctional magnetic resonance imagingBrain functionCo-occurring disordersCognitive aspectsGambling disorderBehavioral addictionsCognitive functionAddictive disordersSubstance addictionDSM-5Substance useNegative consequencesNeurochemical systemsNegative healthVisual representationAddictionSocial consequencesExtant literatureNeurobiologyDisordersCurrent treatment strategiesQuality of lifeMagnetic resonance imagingPositron emission tomographyGambling