2016
Pharmacokinetic Evaluation of the Tau PET Radiotracer 18F-T807 (18F-AV-1451) in Human Subjects
Wooten D, Guehl N, Verwer E, Shoup T, Yokell D, Zubcevik N, Vasdev N, Zafonte R, Johnson K, Fakhri G, Normandin M. Pharmacokinetic Evaluation of the Tau PET Radiotracer 18F-T807 (18F-AV-1451) in Human Subjects. Journal Of Nuclear Medicine 2016, 58: 484-491. PMID: 27660144, PMCID: PMC5334185, DOI: 10.2967/jnumed.115.170910.Peer-Reviewed Original ResearchConceptsDistribution volume ratioTraumatic brain injuryMetabolite-corrected arterial input functionPET imagingPlasma radioactivity concentrationsTemporal cortexDynamic PET imagesTotal volume of distributionVolume of distributionTraumatic brain injury subjectsMesial temporal cortexArterial blood samplesPosterior cingulate gyrusFocal uptakeSUV ratioHuman subjectsArterial input functionPosterior corpus callosumBolus injectionPharmacokinetic evaluation
2008
Estimation from PET data of transient changes in dopamine concentration induced by alcohol: support for a non-parametric signal estimation method
Constantinescu C, Yoder K, Kareken D, Bouman C, O'Connor S, Normandin M, Morris E. Estimation from PET data of transient changes in dopamine concentration induced by alcohol: support for a non-parametric signal estimation method. Physics In Medicine And Biology 2008, 53: 1353-1367. PMID: 18296766, DOI: 10.1088/0031-9155/53/5/012.Peer-Reviewed Original Research
2006
Temporal Resolution of ntPET Using Either Arterial or Reference Region-Derived Plasma Input Functions
Normandin M, Morris E. Temporal Resolution of ntPET Using Either Arterial or Reference Region-Derived Plasma Input Functions. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2006, 2006: 2005-2008. PMID: 17946491, DOI: 10.1109/iembs.2006.259716.Peer-Reviewed Original Research