2022
High-Resolution Structural Brainstem Nuclei: Locus Coeruleus Integrity as Potential Biomarker of Alzheimer’s Disease-Related Phenotypes
Jacobs H, Becker J, Kwong K, Engels-Dominguez N, Prokopiou P, Papp K, Properzi M, Hamptom O, Uquillas F, Sanchez J, Rentz D, Fakhri G, Normandin M, Price J, Bennett D, Sperling R, Johnson K. High-Resolution Structural Brainstem Nuclei: Locus Coeruleus Integrity as Potential Biomarker of Alzheimer’s Disease-Related Phenotypes. Biological Psychiatry 2022, 91: s31. DOI: 10.1016/j.biopsych.2022.02.095.Peer-Reviewed Original Research
2011
Synthesis and evaluation of [18F]exendin (9–39) as a potential biomarker to measure pancreatic β-cell mass
Wang Y, Lim K, Normandin M, Zhao X, Cline GW, Ding YS. Synthesis and evaluation of [18F]exendin (9–39) as a potential biomarker to measure pancreatic β-cell mass. Nuclear Medicine And Biology 2011, 39: 167-176. PMID: 22033026, PMCID: PMC4484741, DOI: 10.1016/j.nucmedbio.2011.07.011.Peer-Reviewed Original ResearchConceptsStandardized uptake valuePositron emission tomography (PET) imagingEmission Tomography ImagingPancreatic β-cell massΒ-cell massTomography imagingInsulin contentGlucagon-like peptide-1 (GLP-1) receptor antagonistGlucagon-like peptide-1Biobreeding diabetes-prone (BB-DP) ratDiabetes-prone ratsVivo positron emission tomography (PET) imagingSprague-Dawley ratsBlood glucose homeostasisReceptor antagonistGlucose homeostasisPeptide-1Time-activity curvesUptake valuePotential biomarkersHigh-resolution research tomographExendin analogsIn-111RatsPostmortem measures