2021
Radiochemical Synthesis and Evaluation in Non-Human Primates of 3‑[11C]methoxy-4-aminopyridine: A Novel PET Tracer for Imaging Potassium Channels in the CNS
Guehl N, Neelamegam R, Zhou Y, Moon S, Dhaynaut M, Fakhri G, Normandin M, Brugarolas P. Radiochemical Synthesis and Evaluation in Non-Human Primates of 3‑[11C]methoxy-4-aminopyridine: A Novel PET Tracer for Imaging Potassium Channels in the CNS. ACS Chemical Neuroscience 2021, 12: 756-765. PMID: 33539063, PMCID: PMC8060895, DOI: 10.1021/acschemneuro.0c00791.Peer-Reviewed Original Research
2014
Initial in vivo PET imaging of 5-HT1A receptors with 3-[(18)F]mefway.
Wooten DW, Hillmer AT, Murali D, Barnhart TE, Thio JP, Bajwa AK, Bonab AA, Normandin MD, Schneider ML, Mukherjee J, Christian BT. Initial in vivo PET imaging of 5-HT1A receptors with 3-[(18)F]mefway. Am J Nucl Med Mol Imaging 2014, 4: 483-9. PMID: 25143866, PMCID: PMC4138142.Peer-Reviewed Original ResearchCaudal anterior cingulate gyrusMesial temporal lobePET radiotracersPET imagingAnterior cingulate gyrusDynamic PET scansVivo PET imagingMale rhesus macaquesBolus injectionCingulate gyrusPET uptakeTemporal lobePET scansLower BPNDLow affinityVivo behaviorCerebellumRhesus macaquesReceptorsSufficient uptakeReference regionSpecific bindingMinutesRadiotracerShorter scan time