ntPET: A New Application of PET Imaging for Characterizing the Kinetics of Endogenous Neurotransmitter Release
Morris ED, Yoder KK, Wang C, Normandin MD, Zheng QH, Mock B, Raymond F, Froehlich JC. ntPET: A New Application of PET Imaging for Characterizing the Kinetics of Endogenous Neurotransmitter Release. Molecular Imaging 2005, 4: 7290.2005.05130. PMID: 16285909, DOI: 10.2310/7290.2005.05130.Peer-Reviewed Original ResearchConceptsNeurotransmitter releaseArterial blood samplingEndogenous neurotransmitter releasePositron emission tomographyEndogenous dopamineDrug treatmentRat striatumBlood samplingBlood flowEmission tomographyFalse-positive responsesD3 receptor ligandsDopamine concentrationsPET imagingReceptor ligandsNoninvasive assayTracer kinetic modelReference regionStimulus conditionsDopamine