2012
Marrow Stromal Cell Infusion Rescues Hematopoiesis in Lethally Irradiated Mice despite Rapid Clearance after Infusion
Yang X, Balakrishnan I, Torok-Storb B, Pillai M. Marrow Stromal Cell Infusion Rescues Hematopoiesis in Lethally Irradiated Mice despite Rapid Clearance after Infusion. Advances In Hematology 2012, 2012: 142530. PMID: 22400029, PMCID: PMC3287024, DOI: 10.1155/2012/142530.Peer-Reviewed Original ResearchTotal body irradiationLethal total body irradiationWild-type C57/BL6 miceC57/BL6 miceEffects of MSCsPromising cellular therapyLethally Irradiated MiceSyngeneic MSCsCell infusionBody irradiationSingle infusionBL6 miceImmune histochemistryInfused MSCsTissue injuryLethal irradiationMarrow stromal cellsIrradiated miceInfusionCellular therapyStromal cellsRapid clearanceMarrow failureRT-PCRMice
2011
Marrow Stromal Cells (MSC) Rescue Hematopoiesis in Lethally Irradiated Mice Despite Rapid Clearance After Infusion,
Yang X, Balakrishnan I, Torok-Storb B, Pillai M. Marrow Stromal Cells (MSC) Rescue Hematopoiesis in Lethally Irradiated Mice Despite Rapid Clearance After Infusion,. Blood 2011, 118: 3406. DOI: 10.1182/blood.v118.21.3406.3406.Peer-Reviewed Original ResearchStem cell transplantationC57/BL6 miceImmune histochemistryBL6 miceInfused MSCsHigh dosesCellular therapyFemale C57/BL6 miceExtra-pulmonary tissuesInfusion of MSCsTime pointsLog-rank testPre-clinical modelsCause of deathTissue injury modelStronger bioluminescent signalReal-time polymerase chain reactionQuantitative real-time polymerase chain reactionSuch cellular therapiesSubsequent time pointsTime polymerase chain reactionHematopoietic systemMesenchymal stromal cellsWhole-body bioluminescentFlt-3 ligand