2023
Decidualization dampens toll-like receptor mediated inflammatory responses in human endometrial stromal cells by upregulating IκBα
Tong M, Scott J, Whirledge S, Abrahams V. Decidualization dampens toll-like receptor mediated inflammatory responses in human endometrial stromal cells by upregulating IκBα. Journal Of Reproductive Immunology 2023, 159: 103988. PMID: 37451159, PMCID: PMC10530124, DOI: 10.1016/j.jri.2023.103988.Peer-Reviewed Original ResearchConceptsEndometrial stromal cellsInflammatory responseStromal cellsHuman endometrial stromal cellsToll-like receptor signalingSex hormone levelsMenstrual cycle stageToll-like receptorsImmune response changesViral double-stranded RNAHuman EnSCsEndometrial responseProinflammatory cytokinesSuccessful pregnancyMenstrual cycleHuman endometriumHormone levelsMajor cell typesImmune responseNFκB p65Viral infectionDecidualizationBacterial lipopolysaccharideReceptor signalingBacterial components
2016
The reduction in circulating levels of melatonin may be associated with the development of preeclampsia
Zeng K, Gao Y, Wan J, Tong M, Lee A, Zhao M, Chen Q. The reduction in circulating levels of melatonin may be associated with the development of preeclampsia. Journal Of Human Hypertension 2016, 30: 666-671. PMID: 27251079, DOI: 10.1038/jhh.2016.37.Peer-Reviewed Original ResearchConceptsIncidence of preeclampsiaLevels of melatoninDevelopment of preeclampsiaSerum levelsPreeclamptic placentasMelatonin receptorsLate-onset preeclampsiaHealthy pregnant womenPregnancy-specific disorderPathogenesis of preeclampsiaHealthy pregnancyPlacental dysfunctionPregnant womenSuccessful pregnancyPreeclampsiaMelatonin levelsPregnancyIncidenceMelatoninOxidative stressWomenTime onsetPlacentaReceptorsAssociation