Enumeration and molecular characterization of circulating tumor cells as an innovative tool for companion diagnostics in breast cancer
Harigopal M, Kowalski D, Vosoughi A. Enumeration and molecular characterization of circulating tumor cells as an innovative tool for companion diagnostics in breast cancer. Expert Review Of Molecular Diagnostics 2020, 20: 815-828. PMID: 32546017, DOI: 10.1080/14737159.2020.1784009.Peer-Reviewed Original ResearchConceptsBreast cancerTumor cellsCTC enumerationCTC detectionCTC clustersMetastatic breast cancerBreast cancer patientsEnumeration of CTCsOverall survivalRisk stratificationMetastatic sitesPeripheral bloodCancer patientsCTC levelsClinical backgroundPrimary siteClinical useCancerTumor phenotypeCompanion diagnosticsTumor heterogeneityDistant sitesMolecular characterizationPatientsPredictive importance